Evidence map›Paper›PMID 40297326›Full record

ReviewMediators of inflammation2025

Cardiac and Digestive Forms of Chagas Disease: An Update on Pathogenesis, Genetics, and Therapeutic Targets.

Amanda Farage Frade, Hélléa Guérin, Joao Paulo Silva Nunes, Luiz Felipe Souza E Silva, Vinicius Moraes de Paiva Roda, Rafael Pedro Madeira, Pauline Brochet, Pauline Andrieux, Jorge Kalil, Christophe Chevillard and 1 more

Abstract readReview
In one paragraph

Review in Mediators of inflammation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Vaccines against chronicExpert review of vaccines · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. A PQQ-dependent oxidoreductase inFrontiers in cellular and infection microbiology · 2026
    Article
  11. Fulminant and fatalASM case reports · 2026
    Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Amanda Farage FradeLaboratory of Immunology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo 05403-900, Brazil.ORCID https://orcid.org/0000-0002-9004-8811
Hélléa GuérinFrench National Institute for Health and Medical Research (INSERM), UMR U1090, TAGC Theories and Approaches of Genomic Complexity, MarMaRa Institute, Aix Marseille University, Marseille 13288, France.ORCID https://orcid.org/0000-0002-5621-3975
Joao Paulo Silva NunesLaboratory of Immunology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo 05403-900, Brazil.ORCID https://orcid.org/0000-0003-4355-6669
Luiz Felipe Souza E SilvaLaboratory of Immunology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo 05403-900, Brazil.ORCID https://orcid.org/0000-0002-3027-8834
Vinicius Moraes de Paiva RodaLaboratory of Immunology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo 05403-900, Brazil.ORCID https://orcid.org/0000-0003-4252-3152
Rafael Pedro MadeiraLaboratory of Immunology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo 05403-900, Brazil.ORCID https://orcid.org/0000-0001-7319-2929
Pauline BrochetFrench National Institute for Health and Medical Research (INSERM), UMR U1090, TAGC Theories and Approaches of Genomic Complexity, MarMaRa Institute, Aix Marseille University, Marseille 13288, France.ORCID https://orcid.org/0000-0002-5812-0385
Pauline AndrieuxFrench National Institute for Health and Medical Research (INSERM), UMR U1090, TAGC Theories and Approaches of Genomic Complexity, MarMaRa Institute, Aix Marseille University, Marseille 13288, France.ORCID https://orcid.org/0000-0002-5154-6340
Jorge KalilLaboratory of Immunology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo 05403-900, Brazil.ORCID https://orcid.org/0000-0001-8415-4274
Christophe ChevillardFrench National Institute for Health and Medical Research (INSERM), UMR U1090, TAGC Theories and Approaches of Genomic Complexity, MarMaRa Institute, Aix Marseille University, Marseille 13288, France.ORCID https://orcid.org/0000-0002-5269-8813
Edecio Cunha-NetoLaboratory of Immunology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo 05403-900, Brazil.ORCID https://orcid.org/0000-0002-3699-3345

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chagas disease, caused by the protozoan parasite

Indexed as

Chagas DiseaseAnimalsChagas CardiomyopathyHumansInterferon-gammaTrypanosoma cruziTumor Necrosis Factor-alphaInterferon-gammaTumor Necrosis Factor-alphacardiomyopathyChagas diseasedigestive formgeneticsmitochondriapathogenesistherapy

Identifiers

PMID40297326
PMCPMC12037249

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.