Evidence map›Paper›PMID 40297713›Full record

ArticleRSC advances2025

Effect of temperature on the carbonization process of cationic carbon dots: a physicochemical and

Nicolás Santos, Paula A Santana, Igor Osorio-Roman, Carlos Jara-Gutiérrez, Joan Villena, Manuel Ahumada

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicolás SantosCentro de Nanotecnología Aplicada, Facultad de Ciencias, Ingeniería y Tecnología, Universidad Mayor Camino La Pirámide 5750, Huechuraba Santiago RM Chile Manuel.ahumada@umayor.cl.ORCID https://orcid.org/0009-0004-1226-2195
Paula A SantanaInstituto de Ciencias Aplicadas, Facultad de Ingeniería, Universidad Autónoma de Chile El Llano Subercaseaux 2801 Santiago San Miguel Chile.ORCID https://orcid.org/0000-0002-5742-4926
Igor Osorio-RomanInstituto de Ciencias Químicas, Facultad de Ciencias, Universidad Austral de Chile Isla Teja s/n Valdivia Región de los Ríos Chile.ORCID https://orcid.org/0000-0001-7502-8698
Carlos Jara-GutiérrezCentro Interdisciplinario de Investigación Biomédica e Ingeniería para la salud (MEDING), Escuela de Kinesiología, Facultad de Medicina, Universidad de Valparaíso Valparaíso Chile.ORCID https://orcid.org/0000-0002-7194-6595
Joan VillenaCentro Interdisciplinario de Investigación Biomédica e Ingeniería para la salud (MEDING), Escuela de Medicina, Facultad de Medicina, Universidad de Valparaíso Valparaíso Chile.ORCID https://orcid.org/0000-0003-3336-1454
Manuel AhumadaCentro de Nanotecnología Aplicada, Facultad de Ciencias, Ingeniería y Tecnología, Universidad Mayor Camino La Pirámide 5750, Huechuraba Santiago RM Chile Manuel.ahumada@umayor.cl.ORCID https://orcid.org/0000-0002-0589-3296

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work highlights the critical role of synthesis conditions in tuning the properties of carbon dots (CDs) for optimized performance in biomedical applications, offering valuable insights into the design of these carbon nanomaterials. Although various synthesis methods and carbon sources have been explored for CD production, few studies have investigated how synthesis temperature modulates and optimizes their physicochemical attributes. In this study, cationic CDs derived from poly(ethylene imine) (PEI) and chitosan (CS) were synthesized using a microwave-assisted hydrothermal method at different temperatures to explore this aspect. It was found that higher carbonization temperatures during the hydrothermal process resulted in smaller, more photoluminescent CDs. This increase in temperature significantly enhanced the biological interactions of the CDs, demonstrating notable biocompatibility. In contrast, the lowest hydrothermal temperature enhanced cytotoxic effects against the Gram-positive pathogen

Identifiers

PMID40297713
PMCPMC12035528

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.