Evidence map›Paper›PMID 40297828›Full record

ArticleFrontiers in veterinary science2025

Zearalenone causes ovarian damage and abnormal estradiol secretion in meat rabbits by inducing oxidative stress and inflammatory responses.

Fengyang Wu, Fengxia Wang, Zhaohong Tang, Xinyu Yang, Yanhua Liu, Man Zhao, Shudong Liu, Shuaijuan Han, Baojiang Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fengyang Wu *College of Animal Science and Technology, Hebei Agricultural University, Baoding, China.
Fengxia Wang *College of Animal Science and Technology, Hebei Agricultural University, Baoding, China.
Zhaohong Tang *Hebei Research Institute of Microbiology Co., Ltd., Baoding, China.
Xinyu YangCollege of Animal Science and Technology, Hebei Agricultural University, Baoding, China.
Yanhua LiuCollege of Animal Science and Technology, Hebei Agricultural University, Baoding, China.
Man ZhaoCollege of Animal Science and Technology, Hebei Agricultural University, Baoding, China.
Shudong LiuCollege of Animal Science and Technology, Hebei Agricultural University, Baoding, China.
Shuaijuan HanCollege of Animal Science and Technology, Hebei Agricultural University, Baoding, China.
Baojiang ChenCollege of Animal Science and Technology, Hebei Agricultural University, Baoding, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zearalenone (ZEA), a prevalent mycotoxin in animal feeds, is known to disrupt normal ovarian development and function due to its estrogenic activity. This study investigates the toxic effects of ZEA on the ovaries of meat rabbits and explores the underlying mechanisms. Ninety healthy 41-day-old Hyla male rabbits were randomly assigned into three groups. The control group received a basal diet, while the experimental groups were fed basal diets supplemented with 300 and 600 μg/kg ZEA, respectively. Each group consisted of 30 replicates, with one rabbit per replicate, and the experimental period lasted 42 days. The results showed that, compared to the control group, the ovarian index was significantly increased in the 600 μg/kg ZEA supplementation group (

Indexed as

inflammatory responsemeat rabbitovaryoxidative stressreproductive hormonezearalenone

Identifiers

PMID40297828
PMCPMC12035730

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.