Evidence map›Paper›PMID 40298323›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2025

TSP-1, TSP-2, and TSP-5 demonstrate sexual dimorphism in intimal hyperplasia in rats and mice.

Ashley A Peters, Furqan Muqri, Corinne Bunn, Mohammed Kassem, Alex Helkin, David Bruch, Kristopher G Maier, Vivian Gahtan

Abstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ashley A PetersStritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States.ORCID 0000-0002-7457-9786
Furqan MuqriDivision of Vascular Surgery and Endovascular Services, SUNY Upstate Medical University, Syracuse, New York, United States.
Corinne BunnStritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States.
Mohammed KassemDivision of Vascular Surgery and Endovascular Services, SUNY Upstate Medical University, Syracuse, New York, United States.ORCID 0009-0007-3021-6047
Alex HelkinDivision of Vascular Surgery and Endovascular Services, SUNY Upstate Medical University, Syracuse, New York, United States.
David BruchDivision of Vascular Surgery and Endovascular Services, SUNY Upstate Medical University, Syracuse, New York, United States.
Kristopher G MaierStritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States.
Vivian GahtanStritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States.ORCID 0000-0003-3602-4904

Funding

The Role of The Thrombospondins In Intimal HyperplasiaR01HL133577 · NHLBI · UPSTATE MEDICAL UNIVERSITY · PI GAHTAN, VIVIAN, MAIER, KRISTOPHER G · 2017 to 2020
$1.3M
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) 133577NHLBI NIH HHS R01 HL133577
6 · The paper itself

Abstract

Thrombospondins (TSPs) are matricellular proteins involved in intimal hyperplasia (IH). We hypothesized that

Indexed as

Carotid Artery InjuriesMuscle, Smooth, VascularMyocytes, Smooth MuscleNeointimaThrombospondin 1ThrombospondinsTunica IntimaAnimalsCell MovementCell ProliferationCells, CulturedChemotaxisDisease Models, AnimalFemaleHyperplasiaMaleThbs1 protein, mouseThbs1 protein, ratThrombospondin 1Thrombospondin 2ThrombospondinsAAVadeno-associated virusintimal hyperplasiasiRNAthrombospondin

Identifiers

PMID40298323
PMCPMC12190619

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.