Evidence map›Paper›PMID 40298354›Full record

ArticleThe Plant journal : for cell and molecular biology2025

Identification of INOSITOL PHOSPHORYLCERAMIDE SYNTHASE 2 (IPCS2) as a new rate-limiting component in Arabidopsis pathogen entry control.

Josephine Mittendorf, Tegan M Haslam, Cornelia Herrfurth, Nicolas Esnay, Yohann Boutté, Ivo Feussner, Volker Lipka

Abstract read
In one paragraph

Article in The Plant journal : for cell and molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Josephine MittendorfDepartment of Plant Cell Biology, Albrecht-von-Haller-Institute for Plant Sciences, Georg-August-University Goettingen, Goettingen, D-37077, Germany.
Tegan M HaslamDepartment of Plant Biochemistry, Albrecht-von-Haller-Institute for Plant Sciences, University of Goettingen, Goettingen, D-37077, Germany.
Cornelia HerrfurthDepartment of Plant Biochemistry, Albrecht-von-Haller-Institute for Plant Sciences, University of Goettingen, Goettingen, D-37077, Germany.
Nicolas EsnayLaboratoire de Biogenèse Membranaire, Université de Bordeaux, UMR5200 CNRS, Villenave d'Ornon, France.
Yohann BouttéLaboratoire de Biogenèse Membranaire, Université de Bordeaux, UMR5200 CNRS, Villenave d'Ornon, France.
Ivo FeussnerDepartment of Plant Biochemistry, Albrecht-von-Haller-Institute for Plant Sciences, University of Goettingen, Goettingen, D-37077, Germany.
Volker LipkaDepartment of Plant Cell Biology, Albrecht-von-Haller-Institute for Plant Sciences, Georg-August-University Goettingen, Goettingen, D-37077, Germany.

Funding

Deutsche Forschungsgemeinschaft HA 10307/1Deutsche Forschungsgemeinschaft INST 186/1167-1Deutsche Forschungsgemeinschaft INST 186/1277-1 FUGGEuropean Research Council Marie Skłodowska Curie Independent Fellowship MSCA-IF-EF-ST:892532
6 · The paper itself

Abstract

INOSITOL PHOSPHORYLCERAMIDE SYNTHASE 2 (IPCS2) is involved in the biosynthesis of complex sphingolipids at the trans-Golgi network (TGN). Here, we demonstrate a role of IPCS2 in penetration resistance against non-adapted powdery mildew fungi. A novel ipcs2

Indexed as

ArabidopsisArabidopsis ProteinsAscomycotaHexosyltransferasesPlant DiseasesGlycosphingolipidsSphingolipidstrans-Golgi NetworkArabidopsis ProteinsGlycosphingolipidsHexosyltransferasesinositolphosphorylceramidephosphatidylinositol-ceramide phosphoinositol transferaseSphingolipidsdisease resistanceendomembrane traffickingpathogen entry controlpowdery mildewsphingolipids

Identifiers

PMID40298354
PMCPMC12039476

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.