Evidence map›Paper›PMID 40298528›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Unlocking the Skin-Protective Effects of

Ceyda Sibel Kılıç, Inês Catarino, Jorge Alves-Silva, Betül Demirci, Damla Kırcı, Lígia Salgueiro, Mónica Zuzarte

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. In Vitro Antifungal and Wound-Healing Potential ofAntibiotics (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ceyda Sibel KılıçAnkara University, Faculty of Pharmacy, Department of Pharmaceutical Botany, 06560 Ankara, Türkiye.
Inês CatarinoUniv Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, Azinhaga de S. Comba, 3000-548 Coimbra, Portugal.
Jorge Alves-SilvaUniv Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, Azinhaga de S. Comba, 3000-548 Coimbra, Portugal.ORCID 0000-0002-5270-3993
Betül DemirciAnadolu University, Faculty of Pharmacy, Department of Pharmacognosy, 26470 Tepebaşı, Eskişehir, Türkiye.ORCID 0000-0003-2343-746X
Damla Kırcıİzmir Katip Çelebi University, Faculty of Pharmacy, Department of Pharmacognosy, 35620 Çiğli, İzmir, Türkiye.
Lígia SalgueiroUniv Coimbra, Faculty of Pharmacy, Azinhaga de S. Comba, 3000-548 Coimbra, Portugal.ORCID 0000-0003-0948-821X
Mónica ZuzarteUniv Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, Azinhaga de S. Comba, 3000-548 Coimbra, Portugal.ORCID 0000-0002-4128-9010

Funding

Fundação para a Ciência e Tecnologia PATCH 022.05810.PTDC.
6 · The paper itself

Abstract

BACKGROUND/

objectivesFungal infections have significant health risks due to virulence factors like biofilms that lead to chronic and persistent infections. To decrease associated rates of morbidity and mortality, it is crucial to develop effective antifungal treatments. The present study aims to evaluate the bioactive potential of

methodsThe minimal inhibitory concentration (MIC) and the minimal lethal concentration (MLC) of five essential oils were assessed on planktonic dermatophytes and the most promising were used to evaluate their effect on the formation and disruption of biofilms, by quantifying biofilm mass using crystal violet and extracellular matrix deposition using safranin staining. Alterations in fungal morphology were confirmed by optical microscopy and a cell migration assay was used to assess wound-healing capacity.

results

conclusionsThe present study provides new insights into the treatment of dermatophytosis by highlighting the antivirulent effects of

Indexed as

biofilmcell migrationdermatophytosisvirulence

Identifiers

PMID40298528
PMCPMC12024059

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.