Evidence map›Paper›PMID 40298616›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Addition of Chlorogenic Acid to Human Semen: Effects on Sperm Motility, DNA Integrity, Oxidative Stress, and

Cinzia Signorini, Roberta Corsaro, Giulia Collodel, Robert Maettner, Karl Sterzik, Erwin Strehler, Laura Liguori, Elena Moretti

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cinzia SignoriniDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-0006-9414
Roberta CorsaroDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-9091-8952
Giulia CollodelDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-1587-0159
Robert MaettnerMVZ Next Fertility Ulm GmbH, 89077 Ulm, Germany.
Karl SterzikMVZ Next Fertility Ulm GmbH, 89077 Ulm, Germany.
Erwin StrehlerMVZ Next Fertility Ulm GmbH, 89077 Ulm, Germany.
Laura LiguoriDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0009-0008-5563-236X
Elena MorettiDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-9467-0501

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the effects of chlorogenic acid (CGA) on human semen and on oxidative stress (OS) induced in vitro in human spermatozoa. After the treatment of the basal semen with 100 µM CGA, rapid and slow sperm progressive motility were evaluated and seminal F

Indexed as

chlorogenic acidDNA integrityF2-Isoprostaneshuman semenNrf2 expressionoxidative stresssperm motility

Identifiers

PMID40298616
PMCPMC12024100

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.