Evidence map›Paper›PMID 40299103›Full record

ArticlePlant cell reports2025

GET3B is involved in chloroplast biogenesis and interacts with the thylakoidal ALB3 and ALB4 insertases.

Uwe Sakamuzi Bodensohn, Beatrix Dünschede, Chiara Kuhlmann, Khushbu Kumari, Roman Ladig, Christopher Grefen, Enrico Schleiff, Donna Fernandez, Danja Schünemann

Abstract read
In one paragraph

Article in Plant cell reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Uwe Sakamuzi BodensohnInstitute for Molecular Biosciences, Goethe University Frankfurt, Max von Laue Str. 9, N200/3.02, 60438, Frankfurt, Germany. Bodensohn@bio.uni-frankfurt.de.ORCID http://orcid.org/0000-0002-4698-3757
Beatrix DünschedeMolecular Biology of Plant Organelles, Ruhr University Bochum, Universitätsstraße 150, 44780, Bochum, Germany.
Chiara KuhlmannMolecular Biology of Plant Organelles, Ruhr University Bochum, Universitätsstraße 150, 44780, Bochum, Germany.
Khushbu KumariMolecular and Cellular Botany, Ruhr University Bochum, Universitätsstraße 150, 44780, Bochum, Germany.
Roman LadigGerman Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
Christopher GrefenMolecular and Cellular Botany, Ruhr University Bochum, Universitätsstraße 150, 44780, Bochum, Germany.
Enrico SchleiffInstitute for Molecular Biosciences, Goethe University Frankfurt, Max von Laue Str. 9, N200/3.02, 60438, Frankfurt, Germany.
Donna FernandezDepartment of Botany, University of Wisconsin-Madison, 430 Lincoln Drive, Madison, WI, 53706-1381, USA.
Danja SchünemannMolecular Biology of Plant Organelles, Ruhr University Bochum, Universitätsstraße 150, 44780, Bochum, Germany.

Funding

Deutsche Forschungsgemeinschaft SCHL 585-10
6 · The paper itself

Abstract

key messageProteomic, functional physiological analyses of get3b mutant plants highlight GET3B's role in chloroplast function. Genetic and interaction analyses indicate get3b and srp54 as mutual potentiators that might share terminal insertases. Protein targeting and insertion into membranes are essential for cellular organization and organelle function. The Guided Entry of Tail-anchored (GET) pathway facilitates the post-translational targeting and insertion of tail-anchored (TA) membrane proteins. Arabidopsis thaliana has four GET3 homologues, including AtGET3B and AtGET3D localized to chloroplasts. These photosynthetic organelles possess complex membrane systems, and the mechanisms underlying their protein targeting and membrane biogenesis are not fully understood. This study conducted a comprehensive proteomic analysis of get3b mutant plastids, which displayed significant alterations. Fluorometric based complex assembly as well as CO

Indexed as

ArabidopsisArabidopsis ProteinsChloroplastsThylakoidsMutationPhotosystem II Protein ComplexALBINO 3 protein, ArabidopsisArabidopsis ProteinsPhotosystem II Protein ComplexALB3ALB4cpSRP54GET3BSTIC1STIC2

Identifiers

PMID40299103
PMCPMC12040988

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.