Evidence map›Paper›PMID 40299212›Full record

SynthesisJournal of gastrointestinal cancer2025

Submucosal Tunneling Endoscopic Resection for Upper Gastrointestinal Subepithelial Lesions: A Systematic Review and Meta-Analysis.

Stavros Chrysovalantis Liapis, Ioannis Baloyiannis, Konstantinos Perivoliotis, Dimitrios Lytras, George Tzovaras

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Journal of gastrointestinal cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stavros Chrysovalantis LiapisDepartment of Surgery, "Achillopouleion" General Hospital, Polymeri 134, 38222, Volos, Greece.ORCID http://orcid.org/0000-0002-2908-9075
Ioannis BaloyiannisDepartment of Surgery, University Hospital of Larissa, Larissa, Greece.ORCID http://orcid.org/0000-0002-6050-3000
Konstantinos PerivoliotisDepartment of Surgery, "Achillopouleion" General Hospital, Polymeri 134, 38222, Volos, Greece. kperi19@gmail.com.ORCID http://orcid.org/0000-0002-6622-5734
Dimitrios LytrasDepartment of Surgery, "Achillopouleion" General Hospital, Polymeri 134, 38222, Volos, Greece.ORCID http://orcid.org/0000-0003-1172-2546
George TzovarasDepartment of Surgery, University Hospital of Larissa, Larissa, Greece.ORCID http://orcid.org/0000-0001-5322-8269

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimSubmucosal tunneling endoscopic resection (STER) is an advanced endoscopic technique used for the minimally invasive removal of subepithelial lesions of the gastrointestinal (GI) tract. The aim of this study was to evaluate the safety and efficacy of STER for upper gastrointestinal subepithelial lesions.

methodsA comprehensive search of major scholar databases (until December 15, 2023) was performed. Complete resection rate was considered the primary outcome. En bloc resection, operation duration, length of stay (LOS), local recurrence, and periprocedural complications were considered secondary outcomes. Random-effects (RE) and fixed-effects (FE) models were used to generate the outcome estimates.

resultsA total of 37 studies and 3795 patients were included. Pooled proportion of complete resection was 99% (95% CI 98.4-99.6%, p < 0.001). En bloc resection was achieved at 87.7% of cases. Overall mean operation duration was 64.2 min, while mean LOS was estimated at 4.93 days. The local recurrence rate was 0.1%. The two most common complications associated with STER were subcutaneous emphysema (5.5%) and pneumothorax (3%).

conclusionSTER is a highly feasible and safe treatment modality for upper GI subepithelial lesions.

Indexed as

Endoscopic Mucosal ResectionGastrointestinal NeoplasmsHumansLength of StayNeoplasm Recurrence, LocalOperative TimePostoperative ComplicationsTreatment OutcomeEndoscopicGastrointestinal, subepithelialResectionSubmucosalTunneling

Identifiers

PMID40299212

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.