Evidence map›Paper›PMID 40299401›Full record

ArticleBiomedicines2025

Macrophage Proangiogenic VEGF-A Is Required for Inflammatory Arteriogenesis During Vascular Injury.

Sheila Sharma, Julia Pierce, Jade C Neverson, Rachel Khan, Cadence F Lee, Saketh Uppuluri, Crystal Parry, Elizabeth Amelotte, Celia A Butler, Frank W Sellke and 4 more

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sheila SharmaVascular Research Laboratory, Providence VA Medical Center, Providence, RI 02908, USA.ORCID 0000-0002-3796-2786
Julia PierceVascular Research Laboratory, Providence VA Medical Center, Providence, RI 02908, USA.ORCID 0000-0003-2755-5543
Jade C NeversonVascular Research Laboratory, Providence VA Medical Center, Providence, RI 02908, USA.
Rachel KhanVascular Research Laboratory, Providence VA Medical Center, Providence, RI 02908, USA.
Cadence F LeeVascular Research Laboratory, Providence VA Medical Center, Providence, RI 02908, USA.ORCID 0000-0002-5437-4273
Saketh UppuluriVascular Research Laboratory, Providence VA Medical Center, Providence, RI 02908, USA.
Crystal ParryVascular Research Laboratory, Providence VA Medical Center, Providence, RI 02908, USA.
Elizabeth AmelotteVascular Research Laboratory, Providence VA Medical Center, Providence, RI 02908, USA.
Celia A ButlerVascular Research Laboratory, Providence VA Medical Center, Providence, RI 02908, USA.
Frank W SellkeVascular Research Laboratory, Providence VA Medical Center, Providence, RI 02908, USA.
Elizabeth O HarringtonVascular Research Laboratory, Providence VA Medical Center, Providence, RI 02908, USA.
Gaurav ChoudharyVascular Research Laboratory, Providence VA Medical Center, Providence, RI 02908, USA.
Alan R MorrisonVascular Research Laboratory, Providence VA Medical Center, Providence, RI 02908, USA.ORCID 0000-0002-2412-7669
Chris S MantsoungaVascular Research Laboratory, Providence VA Medical Center, Providence, RI 02908, USA.ORCID 0000-0003-3494-9081

Funding

Uncoupling of IL-1 beta and VEGF-A Crosstalk Contributes to Impaired Arteriogenesis Response to Ischemia in Chronic Diabetes MellitusP20GM103652 · NIGMS · OCEAN STATE RESEARCH INSTITUTE, INC. · PI HARRINGTON, ELIZABETH O · 2013 to 2022
$21.3M
Pilot Projects ProgramP30GM149398 · NIGMS · OCEAN STATE RESEARCH INSTITUTE, INC. · PI Peng Zhang · 2023 to 2026
$5.5M
Brown Respiratory Research Training ProgramT32HL134625 · NHLBI · BROWN UNIVERSITY · PI Elizabeth O Harrington, Sharon Irene Smith Rounds · 2017 to 2026
$5.1M
Combining Targeted Demethylation with Noncoding RNA-mediated mRNA Stabilization as a Strategy for Therapeutic Arteriogenesis in the AgedR01HL163005 · NHLBI · OCEAN STATE RESEARCH INSTITUTE, INC. · PI MORRISON, ALAN ROSS · 2022 to 2025
$2.3M
Short-Term Training Program to Increase Diversity in Health-Related ResearchR25HL088992 · NHLBI · BROWN UNIVERSITY · PI ABID, RUHUL, DIAZ, JOSEPH A · 2007 to 2024
$1.9M
Development of Rac-Targeted Therapeutic Strategy for Treatment of Calcific AtherosclerosisR01HL139795 · NHLBI · OCEAN STATE RESEARCH INSTITUTE, INC. · PI MORRISON, ALAN ROSS · 2018 to 2022
$1.8M
Role of Endothelial Anoctamin-1 in Pulmonary Arterial HypertensionR01HL148727 · NHLBI · OCEAN STATE RESEARCH INSTITUTE, INC. · PI CHOUDHARY, GAURAV · 2019 to 2022
$1.6M
American Heart Association 23CDA1056587BLRD VA IK2 BX002527CSRD VA I01 CX002231NHLBI NIH HHS R01 HL139795NHLBI NIH HHS R01 HL163005NIGMS NIH HHS P30 GM149398NIH HHS R25HL088992NIH HHS T32HL134625NIH NHLBI R01HL139795NIH NHLBI R01HL148727NIH NHLBI R01HL163005NIH NIGMS P20GM103652NIH NIGMS P30GM149398RI Foundation 16415_139169VA VHA BLR&D IK2BX002527VA VHA CSR&D 1I01CX002231VA VHA CSR&D I01CX001892
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

angiogenesisinflammationmacrophagevascular biologyVEGF-A

Identifiers

PMID40299401
PMCPMC12024885

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.