Evidence map›Paper›PMID 40299696›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Bacterial extracellular vesicles target different bacterial species, impairing cell division and diminishing their pathogenicity.

Yu Kawagishi, Kazunori Murase, Anna Grebenshchikova, Junpei Iibushi, Chang Ma, Teresia M Kimeu, Atsuko Minowa-Nozawa, Takashi Nozawa, Ichiro Nakagawa

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yu KawagishiDepartment of Microbiology, Kyoto University Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.ORCID 0009-0006-0769-000X
Kazunori MuraseDepartment of Microbiology, Kyoto University Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.ORCID 0000-0002-7202-4357
Anna GrebenshchikovaDepartment of Microbiology, Kyoto University Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.ORCID 0009-0003-8848-1880
Junpei IibushiDepartment of Bacteriology I, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
Chang MaDepartment of Microbiology, Kyoto University Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.ORCID 0000-0003-2348-6579
Teresia M KimeuDepartment of Microbiology, Kyoto University Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.ORCID 0009-0000-0846-1432
Atsuko Minowa-NozawaDepartment of Microbiology, Kyoto University Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.
Takashi NozawaDepartment of Microbiology, Kyoto University Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.
Ichiro NakagawaDepartment of Microbiology, Kyoto University Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.

Funding

Japan Agency for Medical Research and Development (AMED) JP22fk0108567s0101MEXT | Japan Science and Technology Agency (JST) JPMJSP2110MEXT | Japan Society for the Promotion of Science (JSPS) 22H04809MEXT | Japan Society for the Promotion of Science (JSPS) 23K06528MEXT | Japan Society for the Promotion of Science (JSPS) 23K18214MEXT | Japan Society for the Promotion of Science (JSPS) 23K24130
6 · The paper itself

Abstract

Extracellular vesicles (EVs) produced by bacteria contain many bacterial-derived molecules, which play an important role in host interactions and as mediators of bacterial communication. However, the role of EVs in interspecies interactions and their physiological and ecological significance are not well understood. In this study, we found that

Indexed as

Cell DivisionEscherichia coliExtracellular VesiclesStreptococcus pyogenesAnimalsMicePeptidoglycanStreptococcal InfectionsVirulencePeptidoglycancell divisionEscherichia coliextracellular vesiclesgroup A Streptococcuspathogenicity

Identifiers

PMID40299696
PMCPMC12067206

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.