Evidence map›Paper›PMID 40299948›Full record

ArticlePLOS global public health2025

Feasibility and effectiveness of tailored interventions for two populations at high-risk of malaria in Senegal: Koranic school children and gold miners.

Sarah Gallalee, Demba Kande, Tidiane Thiam, Henry Ntuku, Caterina Guinovart, Laura Merriman, Abiboulaye Sall, Moustapha Cissé, Aichatou Barry Diouf, Mamadou Diop and 8 more

Abstract read
In one paragraph

Article in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Sarah GallaleeMalaria Elimination Initiative, Institute for Global Health Sciences, University of California San Francisco, San Francisco, California, United States of America.ORCID https://orcid.org/0000-0002-0493-5693
Demba KandePATH Malaria Control and Elimination Partnership in Africa, Dakar, Senegal.ORCID https://orcid.org/0009-0005-5246-1022
Tidiane ThiamPATH Malaria Control and Elimination Partnership in Africa, Dakar, Senegal.ORCID https://orcid.org/0009-0006-9250-5752
Henry NtukuPATH Malaria Control and Elimination Partnership in Africa, Seattle, Washington, United States of America.ORCID https://orcid.org/0000-0001-7218-2710
Caterina GuinovartPATH Malaria Control and Elimination Partnership in Africa, Seattle, Washington, United States of America.ORCID https://orcid.org/0000-0001-8118-2026
Laura MerrimanPATH Malaria Control and Elimination Partnership in Africa, Seattle, Washington, United States of America.
Abiboulaye SallPATH Malaria Control and Elimination Partnership in Africa, Dakar, Senegal.
Moustapha CisséPATH Malaria Control and Elimination Partnership in Africa, Dakar, Senegal.ORCID https://orcid.org/0009-0008-7614-1105
Aichatou Barry DioufMinistère de la Santé et de l'Action Sociale, Dakar, Senegal.
Mamadou DiopMinistère de la Santé et de l'Action Sociale, Dakar, Senegal.
Baba CamaraMinistère de la Santé et de l'Action Sociale, Dakar, Senegal.ORCID https://orcid.org/0009-0008-2733-834X
Niene SeckMinistère de la Santé et de l'Action Sociale, Dakar, Senegal.
Faith De AmaralDivision of HIV, Infectious Diseases, and Global Medicine, Zuckerberg San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America.ORCID https://orcid.org/0000-0002-5583-7671
Roly GoslingMalaria Elimination Initiative, Institute for Global Health Sciences, University of California San Francisco, San Francisco, California, United States of America.ORCID https://orcid.org/0000-0001-6291-0024
Bryan GreenhouseDivision of HIV, Infectious Diseases, and Global Medicine, Zuckerberg San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America.ORCID https://orcid.org/0000-0003-0287-9111
Yakou DieyePATH Malaria Control and Elimination Partnership in Africa, Dakar, Senegal.
Jennifer SmithMalaria Elimination Initiative, Institute for Global Health Sciences, University of California San Francisco, San Francisco, California, United States of America.ORCID https://orcid.org/0000-0002-9244-4412
Adam BennettMalaria Elimination Initiative, Institute for Global Health Sciences, University of California San Francisco, San Francisco, California, United States of America.

Funding

Mentoring translational scientists in international infectious disease researchK24AI144048 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Bryan R Greenhouse · 2019 to 2026
$1.6M
Genetic and social network analysis to target interventions for malaria eliminationK01AI153555 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SMITH, JENNIFER LINNEA · 2020 to 2024
$725k
NIAID NIH HHS K01 AI153555NIAID NIH HHS K24 AI144048
6 · The paper itself

Abstract

Senegal has made significant progress in reducing the malaria burden over the last decade. However, malaria remains a major cause of morbidity in some regions and key challenges exist among high-risk populations who have high exposure to mosquitos, but low coverage and use of vector control measures and limited access to healthcare. Two identified high-risk populations are goldminers and talibés (Koranic school students). We conducted a controlled pre/post survey to measure the impact of targeted malaria interventions, including expansion of active community case management and distribution of LLINs, on reported LLIN usage and Plasmodium falciparum infection prevalence at mining sites and Koranic schools (daaras) during the high transmission season in Senegal. We randomly assigned four health facility catchment areas in Kaolack (a city with many daaras) and four in Saraya (a district with gold mining sites) to intervention or control groups. Surveys were conducted pre (Oct 2021; n = 1740 talibés and gold miners) and post (Feb 2022; n = 2200) delivery of the intervention package to assess intervention coverage and infection prevalence by rapid diagnostic test and qPCR. We compared infection prevalence and self-reported LLIN usage, by group and arm, between the two time periods using a difference in difference framework with binomial generalized linear mixed models. Among the talibés, the package of interventions was associated with an adjusted 12.6-percentage point relative reduction in RDT-derived malaria prevalence (p < 0.05, adjusted risk difference: -12.6, 95% CI: -2.7, -22.4) and an adjusted 44.0-percentage point increase in reported prior night net use (p < 0.001, aRD: 44.0, 95% CI: 36.3, 51.6) in the intervention group compared to the counterfactual. However, among the gold miners there was no measured association between the package of interventions and these outcomes. While there was high acceptability in both groups, interventions should be tailored to address high mobility amongst gold miners and maximize impact.

Identifiers

PMID40299948
PMCPMC12040189

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.