SynthesisBMC oral health2025
Prevalence of xerostomia in patients with type 2 diabetes mellitus: a systematic review and meta-analysis.
Synthesis in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07425275 (The Impact of Integrated Oral Care Intervention Provided by Endocrinologists on Oral Health and Well-being in Diabetes Patients), which is not on this map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Impact of Integrated Oral Care Intervention Provided by Endocrinologists on Oral Health and Well-being in Diabetes Patients
Who cites it
7 citing papers in PubMed.
- Intraglandular injection of amniotic-derived stem cell metabolites enhances submandibular gland regeneration in diabetic male rats.Odontology · 2026Article
- Clinical Implications and Research Progress of Salivary Biomarkers for Endocrine and Metabolic Disorders.Diabetes, obesity & metabolism · 2026Review
- Effectiveness of photobiomodulation in the treatment of xerostomia in type II diabetic patients.Odontology · 2026Article
- Assessment of Anti-M3R antibody in patients with oral lichen planus complaining of xerostomia: a preliminary study.BMC oral health · 2026Article
- Reliable assessment of oral dryness in adults with type 2 diabetes mellitus using the Romanian version of the Summated Xerostomia Inventory.Frontiers in oral health · 2026Article
- Xerostomia as an oral-systemic indicator: Etiology, diagnostic strategies and multimodal management approaches.Bioinformation · 2026Article
- Immediate Effect of Modified Bhramari Pranayama on Salivary Nitric Oxide Level among Type 2 Diabetes Mellitus with Xerostomia: A Randomized Controlled Trial.International journal of yogaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundXerostomia is a common complication associated with diabetes mellitus. However, the prevalence of xerostomia in patients with type 2 diabetes mellitus (T2DM) remains unclear. Therefore, the present study aimed to synthesize results from existing research to investigate the prevalence of xerostomia in T2DM patients.
methodsA comprehensive search was conducted in November 2024 across four databases (PubMed, Scopus, Embase, and Web of Science). The search included English literature pertaining to the prevalence of xerostomia in adult patients with T2DM. Conference proceedings, reviews, and literature lacking complete data or containing other diseases affecting xerostomia prevalence were excluded. Two researchers independently assessed the quality of the included studies by using the Joanna Briggs Institute Standardized Critical Appraisal Checklist. Data analyses were performed using Stata version 18.0 software. A proportions approach was used for meta-analysis. If I
resultsA total of 1355 studies were identified, of which 23 studies encompassing 2486 patients with T2DM met the inclusion criteria. The majority of these studies were small-sample analytical cross-sectional studies using questions about the subjective feeling of oral dryness to assess xerostomia. Risk assessment revealed 2 studies with high risk, 5 with medium risk, and 16 with low risk. The overall prevalence of xerostomia in T2DM patients was 42.49%(95%CI = 36.14-48.46). Subgroup analyses indicated no statistically significant differences based on study design, continent, evaluation tool, disease duration, and HbA1c level.
conclusionsThe lack of high-quality prevalence studies may result in inaccurate estimation of xerostomia prevalence among patients with T2DM. Future research should prioritize large-scale prevalence studies by utilizing more accurate assessment tools. REGISTRATION: PROSPERO [CRD42022315150].
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.