Evidence map›Paper›PMID 40303200›Full record

ArticleKidney international reports2025

Discordant Results Between Creatinine- and Cystatin C-based Equations for Estimating GFR.

Pierre Delanaye, Martin Flamant, Emmanuelle Vidal-Petiot, Jonas Björk, Ulf Nyman, Anders Grubb, Stephan J L Bakker, Martin H de Borst, Marco van Londen, Laurence Derain-Dubourg and 19 more

Erratum issuedAbstract read
In one paragraph

Article in Kidney international reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

29 authors.

Pierre DelanayeDepartment of Nephrology-Dialysis-Transplantation, University of Liège, CHU Sart Tilman, Liège, Belgium.
Martin FlamantAssistance Publique-Hôpitaux de Paris, Bichat Hospital, INSERM U1148, Université Paris Cité and Université Sorbonne Paris Nord, LVTS, Center, Paris, France.
Emmanuelle Vidal-PetiotAssistance Publique-Hôpitaux de Paris, Bichat Hospital, INSERM U1148, Université Paris Cité and Université Sorbonne Paris Nord, LVTS, Center, Paris, France.
Jonas BjörkDivision of Occupational and Environmental Medicine, Lund University, Lund, Sweden.
Ulf NymanDepartment of Translational Medicine, Division of Medical Radiology, Lund University, Malmö, Sweden.
Anders GrubbDepartment of Clinical Chemistry, Skåne University Hospital, Lund University, Lund, Sweden.
Stephan J L BakkerDivision of Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Martin H de BorstDivision of Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Marco van LondenDivision of Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Laurence Derain-DubourgNéphrologie, Dialyse, Hypertension et Exploration Fonctionnelle Rénale, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France.
Andrew D RuleDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.
Björn O EriksenSection of Nephrology, University Hospital of North Norway and Metabolic and Renal Research Group, UiT The Arctic University of Norway, Tromsø, Norway.
Toralf MelsomSection of Nephrology, University Hospital of North Norway and Metabolic and Renal Research Group, UiT The Arctic University of Norway, Tromsø, Norway.
Per-Ola SundinKarla Healthcare Centre, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Natalie EbertCharité Universitätsmedizin Berlin, Institute of Public Health, Berlin, Germany.
Elke SchaeffnerCharité Universitätsmedizin Berlin, Institute of Public Health, Berlin, Germany.
Magnus HanssonFunction Area Clinical Chemistry, Karolinska University Laboratory, Department of Laboratory Medicine, Karolinska University Hospital Huddinge, Karolinska Institute, Stockholm, Sweden.
Karin LittmannDivision of Medicine Huddinge (MedH), Karolinska Institute, Stockholm, Sweden.
Anders LarssonDepartment of Medical Sciences, Clinical Chemistry, Uppsala University, Uppsala, Sweden.
Thomas StehléUniversité Paris Est Créteil, INSERM, Institut Mondor de Recherche Biomédicale, Créteil, France.
Etienne CavalierDepartment of Clinical Chemistry, University of Liège, CHU Sart Tilman, Liège, Belgium.
Justine B BukabauRenal Unit, Department of Internal Medicine, Kinshasa University Hospital, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Ernest K SumailiRenal Unit, Department of Internal Medicine, Kinshasa University Hospital, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Eric YayoDépartement de Biochimie, UFR Sciences Pharmaceutiques et Biologiques, Université Felix Houphouët Boigny, Abidjan, Côte d'Ivoire.
Christophe MariatService de Néphrologie, Dialyse et Transplantation Rénale, Hôpital Nord, CHU de Saint-Etienne, France.
Olivier MoranneDepartment of Nephrology-Dialysis-Apheresis, Hôpital Universitaire Carémeau, Université de Montpellier, Nîmes, France.
Anders ChristenssonDepartment of Nephrology, Skåne University Hospital, Lund University, Malmö, Sweden.
Antoine LanotNormandie Université, Unicaen, CHU de Caen Normandie, Néphrologie, Côte de Nacre Caen, France.
Hans PottelDepartment of Public Health and Primary Care, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Discordant results between cystatin C and creatinine in estimating glomerular filtration rate (GFR) are an important medical issue. However, the equation that should be used when GFR estimates are discordant remains unclear. Methods: This cross-sectional analysis included 15,485 participants with GFR measured by the clearance of an exogenous marker, serum creatinine, and cystatin C. We studied the proportion of discordant results defined as an absolute (> 15 ml/min per 1.73 m Results: In the total cohort, the proportion of subjects with discordant results (absolute or relative) was larger for CKD-EPI (35.1 and 40.6%) than for EKFC (21.9 and 31.7%) or r-LMR (22.8 and 32.8%) equations. Among discrepant results, the proportion of eGFR Conclusion: Based on the lower discrepancy proportion, better balance between eGFR

Indexed as

creatininecystatin Cglomerular filtration rate

Identifiers

PMID40303200
PMCPMC12034923

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.