Evidence map›Paper›PMID 40303597›Full record

ArticleFrontiers in physiology2025

Testosterone levels positively linked to muscle mass but not strength in adult males aged 20-59 years: a cross-sectional study.

Wei Zhang, Zhaohui Cui, Dayong Shen, Li Gao, Qingyun Li

Abstract read
In one paragraph

Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wei Zhang *Department of Neurology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Zhaohui Cui *Department of Orthopedic Surgery, Heze Municipal Hospital, Heze, China.
Dayong ShenDepartment of Neurology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Li GaoDepartment of Endocrinology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Qingyun LiDepartment of Neurology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The relationship between testosterone levels and muscle mass and strength remains contentious. This study aimed to explore the relationship among total serum testosterone levels, muscle mass, and strength in young to middle-aged adults. Methods: The analysis included 4,495 participants (age 39.2 ± 0.2 years, mean ± SE) from the National Health and Nutrition Examination Survey conducted between 2011 and 2014. Weighted regression models were used to assess the association of testosterone levels with muscle mass and strength. Results: For male participants, log Conclusion: Our study indicates that testosterone levels are positively associated with muscle mass but not with muscle strength in young to middle-aged males.

Indexed as

muscle massmuscle strengthNHANESsex differencestestosterone

Identifiers

PMID40303597
PMCPMC12037588

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.