Evidence map›Paper›PMID 40307513›Full record

ReviewNature medicine2025

Precision nutrition for cardiometabolic diseases.

Marta Guasch-Ferré, Clemens Wittenbecher, Marie Palmnäs, Orly Ben-Yacov, Ellen E Blaak, Christina C Dahm, Tove Fall, Berit L Heitmann, Tine R Licht, Marie Löf and 14 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Human-Centered Innovation: Precision Nutrition and the Future of Food.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Advancing Precision Nutrition Through Multimodal Data and Artificial Intelligence.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  14. Review
  15. Review
  16. Article
  17. Advancing personalised and precision nutrition.Journal of nutritional science · 2026
    Review
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Marta Guasch-FerréSection of Epidemiology, Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. marta.guasch@sund.ku.dk.ORCID http://orcid.org/0000-0001-8525-1404
Clemens WittenbecherDepartment of Life Sciences, SciLifeLab, Chalmers University of Technology, Gothenburg, Sweden.ORCID http://orcid.org/0000-0001-7792-877X
Marie PalmnäsDepartment of Life Sciences, SciLifeLab, Chalmers University of Technology, Gothenburg, Sweden.ORCID http://orcid.org/0000-0002-3906-7638
Orly Ben-YacovDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
Ellen E BlaakDepartment of Human Biology, Maastricht University, Maastricht, the Netherlands.ORCID http://orcid.org/0000-0002-2496-3464
Christina C DahmResearch Unit for Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark.
Tove FallDepartment of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0003-2071-5866
Berit L HeitmannResearch Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, The Capital Region, Denmark.
Tine R LichtNational Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID http://orcid.org/0000-0002-6399-9574
Marie LöfDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.ORCID http://orcid.org/0000-0002-2273-4430
Ruth LoosNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-8532-5087
Chirag J PatelDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-8756-8525
Carmelo QuartaUniversity of Bordeaux, INSERM, Neurocentre Magendie, U1215, Bordeaux, France.
Leanne M RedmanPennington Biomedical Research Center, Baton Rouge, LA, USA.
Eran SegalDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0002-6859-1164
Nicola SegataDepartment CIBIO, University of Trento, Trento, Italy.ORCID http://orcid.org/0000-0002-1583-5794
Michael SnyderDepartment of Genetics, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-0784-7987
Qi SunDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID http://orcid.org/0000-0002-8480-1563
Deirdre K TobiasDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID http://orcid.org/0000-0003-0020-9552
Frank B HuDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Paul W FranksDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID http://orcid.org/0000-0002-0520-7604
Rikard LandbergDepartment of Life Sciences, SciLifeLab, Chalmers University of Technology, Gothenburg, Sweden.ORCID http://orcid.org/0000-0002-6399-7608
Jennifer L SargentSchool of Public Health, Imperial College, London, UK.ORCID http://orcid.org/0009-0008-3697-1737
Jordi MerinoNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. jordi.merino@sund.ku.dk.ORCID http://orcid.org/0000-0001-8312-1438

Funding

European Commission (EC) 101161509European Foundation for the Study of Diabetes (EFSD) #0094134Novo Nordisk Fonden (Novo Nordisk Foundation) NNF23SA0084103
6 · The paper itself

Abstract

Precision nutrition is a vibrant and rapidly evolving field of scientific research and innovation with the potential to deliver health, societal and economic benefits by improving healthcare delivery and policies. Advances in deep phenotyping technologies, digital tools and artificial intelligence have made possible early proof-of-concept research that expands the understanding of within- and between-person variability in responses to diet. These studies illustrate the promise of precision nutrition to complement the traditional 'one size fits all' dietary guidelines, which, while considering broad life-stage and disease-specific nutritional requirements, often lack the granularity to account fully for individual variations in nutritional needs and dietary responses. Despite these developments, however, considerable challenges remain before precision nutrition can be implemented on a broader scale. This Review examines the current state of precision nutrition research, with a focus on its application to reducing the incidence and burden of cardiometabolic diseases. We critically examine the evidence base, explore the potential benefits and discuss the challenges and opportunities ahead.

Indexed as

Cardiovascular DiseasesMetabolic DiseasesPrecision MedicineDietHumans

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.