Evidence map›Paper›PMID 40308641›Full record

ArticleFrontiers in nutrition2025

Association between plant-based diets and depression in older adults with heart disease: the mediating role of sleep disturbances.

Yaqun Yu, Yueying Cheng, Nan Cheng, Jie Zhang, Qitao Xu, Yawen Wang, Wei Zhou, Chao Yan, Huiqiong Li, Zhiyun Gong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yaqun YuDepartment of Cardiac Vascular Surgery, The First Medical Center of the People's Liberation Army General Hospital, Beijing, China.
Yueying ChengDepartment of Cardiac Vascular Surgery, The First Medical Center of the People's Liberation Army General Hospital, Beijing, China.
Nan ChengDepartment of Cardiac Vascular Surgery, The First Medical Center of the People's Liberation Army General Hospital, Beijing, China.
Jie ZhangDepartment of Cardiac Vascular Surgery, The First Medical Center of the People's Liberation Army General Hospital, Beijing, China.
Qitao XuDepartment of Cardiac Vascular Surgery, The First Medical Center of the People's Liberation Army General Hospital, Beijing, China.
Yawen WangDepartment of Cardiac Vascular Surgery, The First Medical Center of the People's Liberation Army General Hospital, Beijing, China.
Wei ZhouDepartment of Cardiac Vascular Surgery, The First Medical Center of the People's Liberation Army General Hospital, Beijing, China.
Chao YanDepartment of Cardiac Vascular Surgery, The First Medical Center of the People's Liberation Army General Hospital, Beijing, China.
Huiqiong LiDepartment of Cardiac Vascular Surgery, The First Medical Center of the People's Liberation Army General Hospital, Beijing, China.
Zhiyun GongDepartment of Cardiac Vascular Surgery, The First Medical Center of the People's Liberation Army General Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Depression is not uncommon among older adults with heart diseases and is related to poor prognosis at clinical setting. We aim to explore the association between plant-based diets and depression in older adults with heart disease and further investigate the mediating role of sleep disturbances in this relationship. Methods: A cross-sectional sample of 2039 older adults with heart diseases were recruited from the 2018 Chinese Longitudinal Healthy Longevity Survey (CLHLS). Each individual completed assessments on dietary frequency, depression, sleep quality and duration. Plant-based diet index (PDI), healthy plant-based diet index (hPDI) and unhealthy plant-based diet index (uPDI) were calculated. Logistic regression models and restricted cubic spline curves (RCS) were employed to explore the relationship between plant-based diets and depression in older adults with heart disease. Meanwhile, mediation analysis was used to investigate the mediating roles of sleep quality and sleep duration. Results: The higher the PDI (OR: 0.56, 95% CI: 0.36-0.88) and the hPDI (OR: 0.39, 95% CI: 0.24-0.62), the lower the risk of depression in older adults with heart disease. Conversely, the higher the uPDI, the higher the risk of depression (OR: 1.76, 95% CI: 1.07-2.92). RCS further confirmed a negative linear dose-response relationship between PDI, hPDI and depression in older adults with heart disease, and a positive trend was found between uPDI and depression. Notably, sleep quality (Indirect effect: -0.031, mediated proportion: 61%) partially mediated the relationship between PDI and depression. In the sex-based subgroup analysis, uPDI was only associated with a higher risk of depression in females. Conclusion: This is the first study to suggest a significant negative relationship between plant-based diets and depression in older adults with heart disease. Sleep quality plays a mediating role in the association between plant-based diets and depression. Optimizing the dietary structure and improve sleep quality may help reduce the risk of depression in older adults with heart disease.

Indexed as

cross-sectional studydepressionheart diseaseolder adultsplant-based dietssleep

Identifiers

PMID40308641
PMCPMC12040692

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.