Evidence map›Paper›PMID 40308647›Full record

ArticleHispanic journal of behavioral sciences2025

Neuropsychiatric Symptoms and Mortality in Cognitively Normal Older Mexican Americans.

Phillip A Cantu, Soham Al Snih, Kyriakos Markides, Mukaila Raji

Abstract read
In one paragraph

Article in Hispanic journal of behavioral sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Phillip A CantuUniversity of Texas Medical Branch, Galveston, USA.ORCID 0000-0002-1072-3195
Soham Al SnihUniversity of Texas Medical Branch, Galveston, USA.
Kyriakos MarkidesUniversity of Texas Medical Branch, Galveston, USA.
Mukaila RajiUniversity of Texas Medical Branch, Galveston, USA.

Funding

LONGITUDINAL STUDY OF MEXICAN AMERICAN ELDERLY HEALTHR01AG010939 · NIA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI MARKIDES, KYRIAKOS S · 1992 to 2022
$14.6M
The Texas Resource Center on Minority Aging Research (RCMAR)P30AG059301 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Rebeca Wong · 2018 to 2026
$5.2M
Informant Measures Of Cognitive Decline In MexicoK01AG086589 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Phillip A Cantu · 2024 to 2026
$370k
NIA NIH HHS K01 AG086589NIA NIH HHS P30 AG059301NIA NIH HHS R01 AG010939
6 · The paper itself

Abstract

Neuropsychiatric symptoms (NPS) present in older adults with Alzheimer's disease (AD) and other dementias are related to mortality. Research on the relationship between NPS and mortality in a non-dementia population is limited. This study examines NPS as a predictor of six-year mortality among community dwelling Mexican Americans aged 80 years and older. Data included 466 cognitively normal participants from Wave 7 of the Hispanic Established Population for the Epidemiological Study of Elderly. NPS were measured using the Neuropsychiatric inventory (NPI). Cox proportional hazard models were used to estimate the hazard ratio (HR) of mortality. The HR of death at 6 years was 1.02 (95% Confidence Interval-CI [1.00, 1.04]) as a function of NPI score and 1.09 (95% CI [1.02, 1.17]) for the number of NPI conditions, controlling for demographic and health characteristics. Apathy, irritability, and aberrant motor behavior were all independently predictors of mortality. NPS may be modifiable risk factors to increase survival time or may be indicative of underlying health problems. NPS may be related to underlying health conditions among older adults with normal cognitive functioning.

Indexed as

cognitive functioninghispanic agingmortalityneuropsychiatric inventory

Identifiers

PMID40308647
PMCPMC12040322

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.