Evidence map›Paper›PMID 40309477›Full record

ArticleWorld journal of radiology2025

Structural and temporal dynamics analysis on immune response in low-dose radiation: History, research hotspots and emerging trends.

Shu-Yuan Wang, Jia-Xing Wu, Xian An, Zhen Yuan, Yi-Fan Ren, Xiu-Feng Yu, Xiao-Dong Tian, Wei Wei

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shu-Yuan WangSchool of Medicine, Nankai University, Tianjin 300071, China.
Jia-Xing WuSchool of Medicine, Nankai University, Tianjin 300071, China.
Xian AnSenior Department of Oncology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
Zhen YuanSchool of Medicine, Nankai University, Tianjin 300071, China.
Yi-Fan RenSchool of Medicine, Nankai University, Tianjin 300071, China.
Xiu-Feng YuDepartment of General Medicine, Tuberculosis Hospital of Shaanxi Province, Xi'an 710105, Shaanxi Province, China.
Xiao-Dong TianDepartment of Thoracic Surgery, Chinese PLA General Hospital, Beijing 100853, China.
Wei WeiSenior Department of Oncology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100853, China. dr_weiwei528@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRadiotherapy (RT) is a cornerstone of cancer treatment. Compared with conventional high-dose radiation, low-dose radiation (LDR) causes less damage to normal tissues while potentially modulating immune responses and inhibiting tumor growth. LDR stimulates both innate and adaptive immunity, enhancing the activity of natural killer cells, dendritic cells, and T cells. However, the mechanisms underlying the effects of LDR on the immune system remain unclear.

aimTo explore the history, research hotspots, and emerging trends in immune response to LDR literature over the past two decades.

methodsPublications on immune responses to LDR were retrieved from the Web of Science Core Collection. Bibliometric tools, including CiteSpace and HistCite, were used to identify historical features, active topics, and emerging trends in this field.

resultsAnalysis of 1244 publications over the past two decades revealed a significant surge in research on immune responses to LDR, particularly in the last decade. Key journals such as

conclusionThis bibliometric analysis provides valuable insights into the evolution of studies on responses to LDR, highlights research trends, and identifies emerging areas for further investigation.

Indexed as

Bibliometric analysisImmune responseImmunotherapyLow-dose radiotherapyRadiation-induced immunogenicitySynergistic therapies

Identifiers

PMID40309477
PMCPMC12038408

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.