Evidence map›Paper›PMID 40309479›Full record

ArticleHuman mutation2025

Temperature as a Key Modulator: Investigating Phosphorylation Patterns of p.Asn666

Titas Gladkauskas, Ileana Cristea, Roya Mehrasa, Jean-Baptiste Demoulin, Bjørn Tore Gjertsen, Ove Bruland, Eyvind Rødahl, Cecilie Bredrup

Abstract read
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In one paragraph

Article in Human mutation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Titas GladkauskasDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.ORCID 0009-0002-8595-4489
Ileana CristeaBergen Center for Medical Stem Cell Research, University of Bergen, Bergen, Norway.ORCID 0000-0003-1163-0393
Roya MehrasaDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.ORCID 0000-0003-4090-5114
Jean-Baptiste DemoulinDe Duve Institute, University of Louvain, Brussels, Belgium.ORCID 0000-0002-8016-6689
Bjørn Tore GjertsenDepartment of Internal Medicine, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0001-9358-9704
Ove BrulandDepartment of Medical Genetics, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0002-9943-9034
Eyvind RødahlDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.ORCID 0000-0003-1025-4840
Cecilie BredrupDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.ORCID 0000-0002-2388-0181

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Four different amino acid substitutions have been reported at the p.Asn666 position in platelet-derived growth factor receptor

Indexed as

Receptor, Platelet-Derived Growth Factor betaSignal TransductionTemperatureAmino Acid SubstitutionHumansMutationPhenotypePhosphorylationPDGFRB protein, humanReceptor, Platelet-Derived Growth Factor betagermline activating mutationsPDGFRBreceptor tyrosine kinasetemperature sensitivitythermokinetics

Identifiers

PMID40309479
PMCPMC12041633

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.