Evidence map›Paper›PMID 40310598›Full record

ArticleProbiotics and antimicrobial proteins2026

Protective Effects of Limosilactobacillus reuteri MSMC64 in Hyperlipidemia Rats Induced by a High-Cholesterol Diet.

Wongsakorn Luangphiphat, Praewpannarai Jamjuree, Chantanapa Chantarangkul, Onnicha Amornariyakool, Malai Taweechotipatr

Abstract read
In one paragraph

Article in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Multifunctional antimicrobial effects ofFrontiers in immunology · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wongsakorn LuangphiphatPrincess Srisavangavadhana Faculty of Medicine, Chulabhorn Royal Academy, Bangkok, 10210, Thailand.
Praewpannarai JamjureeCenter of Excellence in Probiotics, Srinakharinwirot University, Bangkok, 10110, Thailand.
Chantanapa ChantarangkulCenter of Excellence in Probiotics, Srinakharinwirot University, Bangkok, 10110, Thailand.
Onnicha AmornariyakoolPrincess Srisavangavadhana Faculty of Medicine, Chulabhorn Royal Academy, Bangkok, 10210, Thailand.
Malai TaweechotipatrCenter of Excellence in Probiotics, Srinakharinwirot University, Bangkok, 10110, Thailand. malai@g.swu.ac.th.

Funding

Center of Excellence in Probiotics at Srinakharinwirot University 324/2565
6 · The paper itself

Abstract

Hyperlipidemia, characterized by abnormally elevated levels of lipids such as cholesterol, is a significant risk factor for cardiovascular diseases (CVD), contributing to increased oxidative stress, inflammation, and disruption of gut immunity. Dysbiosis, or imbalance in the gut microbiome, plays a critical role in the pathogenesis of hyperlipidemia. Probiotics, as key components of the gut microbiome, have been shown to positively impact health. This study aimed to evaluate the effects of Limosilactobacillus reuteri MSMC64 on lipid profiles, blood glucose levels, hepatic steatosis, antioxidant capacity, inflammatory biomarkers, and colon barrier immunity in hyperlipidemic rats induced by a high-cholesterol diet. The results demonstrated that the administration of L. reuteri MSMC64 may improve lipid profiles and blood glucose levels, reduce hepatic steatosis and oxidative stress, and lower inflammatory biomarkers while maintaining colon barrier integrity. These findings suggest that L. reuteri MSMC64 has the potential to be developed as a probiotic supplement for mitigating risk factors associated with hyperlipidemia and CVD.

Indexed as

HyperlipidemiasLimosilactobacillus reuteriProbioticsAnimalsCholesterolDiet, High-FatGastrointestinal MicrobiomeMaleOxidative StressRatsRats, Sprague-DawleyCholesterolCardiovascular diseaseHyperlipidemiaLimosilactobacillus reuteriMetabolic disease

Identifiers

PMID40310598
PMCPMC12999743

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.