Trial reportJournal of the International Society of Sports Nutrition2025
Physiological effects of spirulina supplementation during lactate threshold exercise at simulated altitude (2,500 m): a randomized controlled trial.
Trial report in Journal of the International Society of Sports Nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
backgroundExisting literature indicates that spirulina supplementation can improve a variety of blood morphological parameters (such as hemoglobin) in healthy and clinical populations. Given the importance of hemoglobin for endurance exercise, particularly at altitude, this study aimed to investigate whether spirulina supplementation can improve blood morphological parameters in healthy cyclists and positively influence physiological variables when completing a lactate threshold test at simulated moderate altitude (2,500 m).
methodsTwenty (18 male; 2 female) healthy participants (Mean ± SD; Age 37 ± 9 years, Stature 181 ± 6 cm, Mass 81 ± 9 kg,
resultsFollowing spirulina supplementation, heart rate at the lactate threshold was significantly lower in comparison to placebo supplementation (spirulina = 152 ± 11 b.min -1 vs. placebo = 155 ± 12 b.min -1,
conclusionIn conclusion, three weeks of spirulina supplementation at 6 g/day reduced heart rate during a lactate threshold test at a simulated moderate altitude (2,500 m), but did not produce additional physiological or hematological benefits.
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