ArticleNature biomedical engineering2025
Magnetically driven biohybrid blood hydrogel fibres for personalized intracranial tumour therapy under fluoroscopic tracking.
Article in Nature biomedical engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- A magnetic nanorobot with guided aggregation and thrombin-triggered coagulation for endovascular embolization.Materials today. Bio · 2026Article
- A ciliated intravascular soft millirobot for multimodal in-flow collective manipulation.Science advances · 2026Article
- CD5Science advances · 2026Article
- 3D Printing of Magnetic Soft Materials for Functional Structures and Devices.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Multi-Legged Magnetic Soft Robot for On-Demand Targeted Delivery in Pulmonary Environments.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Technology roadmap from fiber materials to fiber electronics.National science review · 2026Review
- A Multimodal Magnetically Driven Soft Robot With Integrated Actuation-Sensing Based on Photothermal Reprogramming Technology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Anisotropic Hydrogel Fibers for Soft Robotics: From Structural Engineering to Multi-Responsive Actuation.Gels (Basel, Switzerland) · 2026Review
- Adaptive gyration mechanism in fan worm gill filaments for enhanced filter-feeding efficiency.Fundamental research · 2026Article
- Redox- and Photo-Responsive FeACS applied materials & interfaces · 2026Article
- Chemotactic Gold Nanozyme-Powered Flasklike Pentosan Nanobots for Tumor-Specific Drug Delivery.Advanced healthcare materials · 2026Article
- Deployment and clearance of microrobots for localized therapy: past, present and future.National science review · 2026Review
- Magnetic medical microrobots with memory-capable genetic circuits.Science advances · 2026Article
- All-in-one optically interactive soft robots with embedded liquid crystal holography.Light, science & applications · 2026Article
- Genetically engineered human cell-based microrobots for selective cancer cell death.Science advances · 2026Article
- A new paradigm for brain-machine interface electrodes: From static to dynamic, advancing toward embodied intelligence.Innovation (Cambridge (Mass.)) · 2026Review
- Liquid Metal Microrobots for Magnetically Guided Transvascular Navigation.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Microrobotic copper-rich electrochemical interfacing for targeted cancer theranostics in the gut.Science advances · 2026Article
- Biodegradable Adhesive Systems for Bio-Integrated Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Small materials with pliability and untethered mobility are particularly suitable for minimally invasive medical interventions inside the body. However, the capabilities and applicability of such soft 'robots' are restricted by foreign-body responses to them and by the need to get them cleared from the body after the intervention. Here we report the development of biodegradable magnetized biohybrid blood hydrogel fibres that evade immune recognition, and their applicability for targeted intracranial tumour therapy with real-time tracking through X-ray fluoroscopy. The gel fibres can be made of the patient's own blood mixed with a small amount of magnetic particles and can be produced in about 15 min. We show that the locomotion of intracranially injected gel fibres through cerebrospinal fluid can be remotely controlled under a magnetic field and fluoroscopically tracked, and that a drug encapsulated in the gels can be released on demand under magnetic control, as we show for the delivery of doxorubicin to intracranial tumours in the minipigs. Biodegradable soft actuatable materials that avoid foreign-body responses may aid the development of personalized targeted interventions.
Indexed as
Identifiers
40312457What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.