Evidence mapPaperPMID 40312693Full record

Trial reportEuropean journal of medical research2025

Effects of anesthetic nasal masks on hypoxemia in overweight/obese patients undergoing gastroscopy: a randomized controlled trial.

Huan Liu, Peipei Guo, Lijian Chen, Xuesheng Liu, Huisheng Wu

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Huan LiuDepartment of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, 230022, Anhui Province, China.
Peipei GuoDepartment of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, 230022, Anhui Province, China.
Lijian ChenDepartment of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, 230022, Anhui Province, China.
Xuesheng LiuDepartment of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, 230022, Anhui Province, China. liuxuesheng@ahmu.edu.cn.
Huisheng WuDepartment of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, 230022, Anhui Province, China. zn000482@whu.edu.cn.

Funding

Research Fund Project of Anhui Medical University 2022xkj140Research Fund Project of Anhui Medical University 2022xkj148Science Research Fund of Colleges and University in Anhui Province 2022AH051187
6 · The paper itself

Abstract

backgroundOverweight and obese patients are at a higher risk of hypoxemia during sedated gastroscopy due to impaired respiratory function. The aim of this study was to investigate whether an anesthetic nasal mask could have a positive outcome in preventing hypoxemia in such patients compared with a conventional nasal catheter.

methodsThis prospective, randomized controlled trial enrolled 146 overweight/obese patients (BMI ≥ 25 kg/m

resultsOf the 146 patients, 73 were assigned to the nasal mask group and 73 to the nasal cannula group. The incidence of hypoxemia was significantly lower in the nasal mask group (13.7%) compared with the nasal cannula group (37.0%; absolute risk reduction [ARR] = 23.3%, 95% CI 9.7-36.9%%, p = 0.002; relative risk reduction [RRR] = 63.0%). In addition, the nasal mask group required fewer rescue airway interventions, such as jaw thrusts and noninvasive ventilation. No significant differences were observed in adverse events between the two groups.

conclusionsNasal masks significantly reduce hypoxemia (with a 63% relative risk reduction) and the need for airway interventions during sedated gastroscopy in overweight/obese patients, without increasing adverse events. These findings support the use of nasal masks as an effective and safe airway management strategy for this patient population. Clinical trial registration number ChiCTR2100053388.

Indexed as

GastroscopyHypoxiaMasksObesityOverweightAdultAgedFemaleHumansMaleMiddle AgedProspective StudiesGastroscopyHypoxemiaNasal cannulaNasal maskObesityOverweight

Identifiers

PMID40312693
PMCPMC12046643

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.