Evidence mapPaperPMID 40313185Full record

ArticleACS nano2025

Berberine-Functionalized Bismuth-Doped Carbon Dots in a Pathogen-Responsive Hydrogel System: A Multifaceted Approach to Combating Periodontal Diseases.

Xuan Li, Regina Huang, Pugeng Li, Fung Kit Tang, Jing He, Hanyu Sun, Xiaoyu Wang, Miao Wang, Xinmiao Lan, Xinna Wang and 8 more

Abstract read
In one paragraph

Article in ACS nano, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Frontiers in cellular and infection microbiology · 2026
    Article
  6. Review
  7. Review
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Xuan LiFaculty of Dentistry, The University of Hong Kong, Hong Kong SAR 999077, PR China.ORCID 0000-0003-3785-5507
Regina HuangFaculty of Dentistry, The University of Hong Kong, Hong Kong SAR 999077, PR China.
Pugeng LiHospital of Stomatology, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou 510055, PR China.
Fung Kit TangFaculty of Dentistry, The University of Hong Kong, Hong Kong SAR 999077, PR China.
Jing HeFaculty of Dentistry, The University of Hong Kong, Hong Kong SAR 999077, PR China.
Hanyu SunHospital of Stomatology, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou 510055, PR China.
Xiaoyu WangHospital of Stomatology, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou 510055, PR China.
Miao WangFaculty of Dentistry, The University of Hong Kong, Hong Kong SAR 999077, PR China.
Xinmiao LanBeijing Area Major Laboratory of Peptide and Small Molecular Drugs, Engineering Research Centre of Ministry of Education of China, Beijing Laboratory of Biomedical Materials, School of Pharmaceutical Science, Capital Medical University, Beijing 100069, PR China.ORCID 0000-0002-7503-6310
Xinna WangDepartment of Mechanical Engineering, The University of Hong Kong, Hong Kong SAR 999077, PR China.
Sarah Sze Wah WongImmunology of Fungal Infections Unit, Institut Pasteur, Paris 75015, France.
Lijian JinFaculty of Dentistry, The University of Hong Kong, Hong Kong SAR 999077, PR China.ORCID 0000-0002-5340-9710
Ken Cham-Fai LeungDepartment of Chemistry, The Hong Kong Baptist University, Kowloon, Hong Kong SAR 999077, PR China.ORCID 0000-0002-0349-0418
Hai Ming WongFaculty of Dentistry, The University of Hong Kong, Hong Kong SAR 999077, PR China.ORCID 0000-0003-3411-6442
Sheng WangState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, PR China.
Lanping GuoState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, PR China.
Pei-Hui DingStomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Hangzhou 310006, PR China.
Xiaolin YuHospital of Stomatology, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou 510055, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontal disease, a global health burden linked to dysbiotic oral polymicrobial communities and disrupted immune-inflammatory responses, is critically mediated by

Indexed as

Anti-Bacterial AgentsBerberineBismuthCarbonHydrogelsPeriodontal DiseasesPorphyromonas gingivalisQuantum DotsAnimalsHumansMiceAnti-Bacterial AgentsBerberineBismuthCarbonHydrogelsalveolar bone lossimmune-responses modulationpathogen-responsive hydrogelperiodontitissubgingival microbiota

Identifiers

PMID40313185
PMCPMC12080333

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.