Evidence map›Paper›PMID 40313437›Full record

ReviewCureus2025

Impact of Lifestyle Modifications Along With Pharmacological Treatment of Heart Failure: A Narrative Review.

Elizabeth Caroline Palaparthi, Priyanka K, Arockiamary Ignasimuthu, Gaoudam N, Nagasaikaran Sade, Naveen Bade, Bharath Kumar Jakka, Khyathi Krishna Gogineni, Anjaneyulu Dunde, Tambi Medabala and 1 more

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elizabeth Caroline PalaparthiDepartment of Internal Medicine, Shasta Regional Medical Center - Prime Healthcare, Redding, USA.
Priyanka KDepartment of Obstetrics and Gynecology, Vinayaka Mission's Kirupananda Variyar Medical College and Hospitals, Vinayaka Mission's Research Foundation (Deemed to be University), Salem, IND.
Arockiamary IgnasimuthuDepartment of Medical Surgical Nursing, Faculty of Health Sciences, Villa College, Malé, MDV.
Gaoudam NDepartment of Medical Surgical Nursing, Vinayaka Mission's College of Nursing, Vinayaka Mission's Research Foundation (Deemed to be University), Karaikal, IND.
Nagasaikaran SadeDepartment of Internal Medicine, Apollo Institute of Medical Sciences and Research, Hyderabad, IND.
Naveen BadeDepartment of Nephrology, Northeast Alabama Regional Medical Center, Anniston, USA.
Bharath Kumar JakkaDepartment of Internal Medicine, Baptist Medical Center South, Montgomery, USA.
Khyathi Krishna GogineniDepartment of Stroke Medicine, Stepping Hill Hospital, Stockport, GBR.
Anjaneyulu DundeDepartment of Internal Medicine, Baptist Medical Center South, Montgomery, USA.
Tambi MedabalaDepartment of Physiology, Netaji Subhas National Institute of Sports, Sports Authority of India, Patiala, IND.
Panneerselvam PeriasamyDepartment of Physiology, Government Erode Medical College and Hospital, Erode, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure (HF) remains a leading cause of morbidity and mortality worldwide. While pharmacological therapy is foundational, lifestyle modifications are increasingly recognised for their complementary role. This narrative review explores the synergistic effects of lifestyle interventions, combined with pharmacological treatment, in HF management. A literature search (2000-2025) was conducted using PubMed, Scopus, Cochrane, and Google Scholar, to identify studies on integrative approaches to HF care. Lifestyle changes, such as dietary modification, exercise, weight management, smoking and alcohol cessation, and psychosocial support, enhance the efficacy of standard therapies, improve quality of life, and reduce hospitalisations. Integration with medications, like renin-angiotensin-aldosterone system (RAAS) inhibitors, beta-blockers, and sodium-glucose cotransporter-2 (SGLT2) inhibitors, shows improved neurohormonal balance, reduced inflammation, better endothelial function, and delayed cardiac remodelling. However, socioeconomic and cultural barriers challenge real-world implementation. Combining lifestyle interventions with pharmacotherapy provides a holistic, patient-centred strategy for HF management. Future efforts should focus on personalised care, multidisciplinary teams, and policy support, to improve adherence and outcomes.

Indexed as

heart failureheart failure managementintegrative approachlifestyle modificationspharmacological treatment

Identifiers

PMID40313437
PMCPMC12045463

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.