Evidence map›Paper›PMID 40313594›Full record

ArticleBJUI compass2025

Association of overactive bladder with all-cause and cardiovascular mortality in women: A propensity-matched NHANES study.

Weipu Mao, Sagar Barge, Zhaobo Luo, Weiqun Yu

Abstract read
In one paragraph

Article in BJUI compass, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Weipu MaoDepartment of Medicine, Beth Israel Deaconess Medical Center Harvard Medical School Boston Massachusetts USA.
Sagar BargeDepartment of Medicine, Beth Israel Deaconess Medical Center Harvard Medical School Boston Massachusetts USA.
Zhaobo LuoDepartment of Medicine, Beth Israel Deaconess Medical Center Harvard Medical School Boston Massachusetts USA.
Weiqun YuDepartment of Medicine, Beth Israel Deaconess Medical Center Harvard Medical School Boston Massachusetts USA.

Funding

Cav1.2 in bladder physiology and pathologyR01DK135672 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI weiqun yu · 2024 to 2026
$1.6M
Role of Ectonucleotidase in Voiding Function and DysfunctionR01DK126674 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI YU, WEIQUN · 2021 to 2024
$1.5M
NIDDK NIH HHS R01 DK126674NIDDK NIH HHS R01 DK135672
6 · The paper itself

Abstract

Objectives: To examine the impact of overactive bladder (OAB) on all-cause and cardiovascular mortality in women in a real-world setting, and to examine the association of TyG-related indices with OAB. Methods: Data on 6580 women aged ≥20 years were collected from the National Health and Nutrition Examination Survey (NHANES) database. Kaplan-Meier curves and Cox survival analysis were used to evaluate the association between OAB and all-cause and cardiovascular mortality. Biomarkers for metabolic syndrome were assessed for their association with OAB, including triglyceride-glucose (TyG) and TyG-related indices. The association between TyG-related indices and OAB was evaluated using restricted cubic splines (RCS), receiver operating characteristic (ROC) curves and multivariate logistic regression, with propensity score matching (PSM) employed to balance confounders between OAB and non-OAB groups. Results: Kaplan-Meier curves showed that OAB was associated with a poorer prognosis, and multivariate Cox regression analyses indicated that OAB was an independent risk factor for both all-cause and cardiovascular mortality. RCS revealed a positive association between TyG-related indices and OAB. Both ROC curves and multivariate logistic regression analysis indicated that TyG-WHtR (TyG combined with waist-to-height ratio) was strongly associated with OAB, with a higher TyG-WHtR associated with an increased risk of OAB. The retrospective design and selection bias may be the potential limitations. Conclusions: OAB is positively associated with all-cause and cardiovascular mortality in women. TyG-related indices are positively associated with OAB, with TyG-WHtR as the most effective index.

Indexed as

all‐cause mortalitycardiovascular mortalityoveractive bladderpropensity score matchingtriglyceride‐glucose index

Identifiers

PMID40313594
PMCPMC12040721

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.