ArticleAmerican journal of respiratory and critical care medicine2025
STAT3-Dependent Regulation of CFTR and Ciliogenesis Is Essential for Mucociliary Clearance and Innate Airway Defense in Hyper-IgE Syndrome.
Abstract read
In one paragraph
Article in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Clinical features, genetics, treatment, and long-term outcomes of STAT3 hyper-IgE syndrome: Single-center cohort analysis.The Journal of allergy and clinical immunology · 2026Observational
- How I Treat: Infections and inborn errors of immunity-Prevention, diagnosis, and treatment.Journal of human immunity · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
40 authors.
Ling SunMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Samantha A WallsMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Hong DangMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Nancy L QuinneyMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Patrick R SearsMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Taraneh SadritabriziMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Koichi HasegawaMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Kenichi OkudaMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.ORCID 0000-0001-9341-2730
Takanori AsakuraMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Xiuya ChangDepartment of Biostatistics, University of North Carolina Gillings School of Global Public Health, Chapel Hill, North Carolina.
Meiqi ZhengMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Yu MikamiMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Felicia U DizmondMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Daniela DanilovaMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Lynn ZhouMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Anshulika DeshmukhMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Deborah M CholonMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Giorgia RadicioniMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Troy D RogersMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
William J KissnerMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Matthew R MarkovetzMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Tara N Guhr LeeMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Mark I GutayMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Charles R EstherMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.ORCID 0000-0002-8081-2986
Michael ChuaMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Barbara R GrubbMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Camille EhreMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Mehmet KesimerMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
David B HillMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Lawrence E OstrowskiMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Brian ButtonMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Martina GentzschMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Chevalia RobinsonNational Heart, Lung and Blood Institute and.
Kenneth N OlivierMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Alexandra F FreemanNational Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland; and.
Scott H RandellMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Eszter VladarDivision of Pulmonary Sciences and Critical Care, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Wanda K O'NealMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Richard C BoucherMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Gang ChenMarsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, and.
Funding
Vector CoreP30DK065988 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Scott H Randell · 2004 to 2026
$26.5MThe Biophysics of Mucus Hydration and Adhesion/CohesionP01HL108808 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOUCHER, RICHARD CHARLES · 2012 to 2021
$23.9MProject 4: Biophysical and structural characterization of airway submucosal gland mucus in health and diseaseP01HL164320 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Richard Charles Boucher, Michael Rubinstein · 2022 to 2026
$13.9MFunctional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to PhenotypeR01HL117836 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI OSTROWSKI, LAWRENCE E · 2013 to 2023
$4.4MThe role of mucus and pulmonary surface interactions in lung defenseR01HL125280 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUTTON, BRIAN M · 2015 to 2023
$3.1MThe molecular and cellular mechanisms of the STAT3 mutation-mediated pulmonary disorder in Autosomal Dominant Hyper IgE Syndrome (AD-HIES)U01HL156655 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOUCHER, RICHARD CHARLES, CHEN, GANG · 2022 to 2025
$3.0MMucociliary innate defense mechanism in the human distal airwayR01HL163602 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Kenichi Okuda · 2023 to 2026
$2.4MCLC NIH HHS Bench-to-BedsideCystic Fibrosis Foundation CFF003045F221-SUNCystic Fibrosis Foundation CFF BOUCHE19R0Cystic Fibrosis Foundation CFF HILL20Y2-OUTCystic Fibrosis Foundation CFF RDP ESTHER24R0Cystic Fibrosis Foundation CHEN18G0Cystic Fibrosis Foundation ESTHER22Y2-SVCNHLBI NIH HHS Intramural Research ProgramNHLBI NIH HHS P01 HL108808NHLBI NIH HHS P01 HL164320NHLBI NIH HHS R01 HL117836NHLBI NIH HHS R01 HL125280NHLBI NIH HHS R01 HL163602NHLBI NIH HHS U01 HL156655NIDDK NIH HHS P30 DK065988North Carolina Children's Hospital Chen2021
Abstract
PubMed holds no abstract for this paper.
Indexed as
CiliaCystic Fibrosis Transmembrane Conductance RegulatorImmunity, InnateJob SyndromeMucociliary ClearanceSTAT3 Transcription FactorFemaleHumansMaleMutationSputumCystic Fibrosis Transmembrane Conductance RegulatorSTAT3 protein, humanSTAT3 Transcription Factorairway host defenseCFTRhyper-IgE syndromemucociliary clearanceSTAT3
Identifiers
What Socratic holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.