ArticleCell metabolism2025
Nicotinic acid riboside maintains NAD
Erratum issuedAbstract read
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Article in Cell metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Metabolic Crosstalk Between Host and Tumor as a Circuit of Resilience in Cancer Therapy.Cells · 2026Review
- Double-Pronged NAD Preservation: Delaying Cellular Senescence and Initiating Musculoskeletal Regeneration.Aging cell · 2026 · on this mapArticle
- Transcriptomic and experimental identification of immune- and telomere-related genes in pelvic organ prolapse.Frontiers in pharmacology · 2026Article
- Disruption of Gut Microbiota-Mediated De Novo NADAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Altered nicotinamide adenine dinucleotide metabolism drives cartilage degeneration and osteoarthritis.Clinical and translational medicine · 2025Article
- Cross-talk between aging resilience pathways and autoimmunity onset.Frontiers in immunology · 2025Review
Corrections and comments
- Erratum issued
Authors and funding
27 authors.
Won-Suk SongDepartment of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Xiyu ShenDepartment of Medicine, Physiology and Biophysics, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Kang DuDepartment of Medicine, Physiology and Biophysics, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Cuauhtemoc B RamirezDepartment of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA; Department of Microbiology and Molecular Genetics, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Sang Hee ParkDepartment of Medicine, Physiology and Biophysics, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Yang CaoDepartment of Medicine, Physiology and Biophysics, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Johnny LeDepartment of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Hosung BaeDepartment of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Joohwan KimDepartment of Microbiology and Molecular Genetics, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Yujin ChunDepartment of Microbiology and Molecular Genetics, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Nikki Joyce KhongDepartment of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Marie KimDepartment of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Sunhee JungDepartment of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Wonsuk ChoiDepartment of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Miranda L LopezDepartment of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Zaid SaidDepartment of Medicine, Physiology and Biophysics, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Zehan SongDepartment of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720, USA.
Sang-Guk LeeDepartment of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA; Department of Laboratory Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, South Korea.
Dequina NicholasDepartment of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA; Department of Molecular Biology and Biochemistry, University of California, Irvine, School of Biological Sciences, Irvine, CA 92697, USA.
Yo SasakiDepartment of Genetics, Washington University School of Medicine, Saint Louis, MO 63110, USA.
Jeffrey MilbrandtDepartment of Genetics, Washington University School of Medicine, Saint Louis, MO 63110, USA.
David K ImagawaDivision of Vascular and Endovascular Surgery, Department of Surgery, University of California, Irvine, Orange, CA 92868, USA.
Dorota Skowronska-KrawczykDepartment of Physiology and Biophysics, Department of Ophthalmology, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Danica ChenDepartment of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720, USA.
Gina LeeDepartment of Microbiology and Molecular Genetics, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA.
Cholsoon JangDepartment of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA. Electronic address: choljang@uci.edu.
Qin YangDepartment of Medicine, Physiology and Biophysics, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA. Electronic address: qin.yang@uci.edu.
Funding
Institute for Clinical and Translational ScienceUM1TR004927 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI DAN M COOPER, Eric J. Vilain · 2024 to 2026
$12.2MCARCINOGENESIST32CA009054 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI EDINGER, AIMEE L, FRUMAN, DAVID ALEXANDER · 1985 to 2025
$8.6MEpigenetic Regulation of Mitochondrial Homeostasis and Energy MetabolismR01DK121146 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI Qin Yang · 2019 to 2026
$3.5MAlternative polyadenylation as a novel mechanism for diabetesR01DK136940 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI Qin Yang · 2023 to 2026
$2.9MSex Differences in lipid antigen presentation, impact of lipid antigen presentation on peripheral lipid metabolismDP2AI171121 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI Dequina Angelina Nicholas · 2022 to 2026
$2.8MElucidating dietary fructose and alcohol interactions during liver cancer developmentR01AA029124 · NIAAA · UNIVERSITY OF CALIFORNIA-IRVINE · PI JANG, CHOLSOON · 2021 to 2025
$2.0MInflammation and Aging-associated DiabetesR01AG063389 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI CHEN, DANICA · 2019 to 2023
$2.0MNutrient Sensing, Hematopoietic Stem Cell Metabolism and AgingR01AG063404 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI CHEN, DANICA · 2018 to 2022
$2.0MNeural Stem Cell Aging and NeurodegenerationR01AG082105 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI DANICA CHEN · 2024 to 2026
$1.7MElucidating the regulation of RNA methylation by mTOR signaling in cancerK22CA234399 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI LEE, GINA · 2022 to 2023
$440kElucidating alcohol-induced metabolic remodeling of critical organsR21AA030358 · NIAAA · UNIVERSITY OF CALIFORNIA-IRVINE · PI JANG, CHOLSOON, SELDIN, MARCUS MICHAEL · 2023 to 2023
$412kElucidating the role of nonessential amino acid metabolism in diabetic skin woundsF31DK134173 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI Johnny Le · 2023 to 2026
$197kNCATS NIH HHS UM1 TR004927NCI NIH HHS K22 CA234399NCI NIH HHS T32 CA009054NIAAA NIH HHS R01 AA029124NIAAA NIH HHS R21 AA030358NIAID NIH HHS DP2 AI171121NIA NIH HHS R01 AG063389NIA NIH HHS R01 AG063404NIA NIH HHS R01 AG082105NIDDK NIH HHS F31 DK134173NIDDK NIH HHS R01 DK121146NIDDK NIH HHS R01 DK136940
Abstract
Liver-derived circulating nicotinamide from nicotinamide adenine dinucleotide (NAD
Indexed as
AgingHomeostasisNADNiacinamide5'-NucleotidaseAnimalsKidneyLiverMaleMiceMice, Inbred C57BLMice, KnockoutNicotinamide-Nucleotide AdenylyltransferasePhosphotransferases (Alcohol Group Acceptor)Pyridinium Compounds5'-NucleotidaseNADNiacinamidenicotinamide-beta-ribosideNicotinamide-Nucleotide AdenylyltransferaseNmnat1 protein, mousePhosphotransferases (Alcohol Group Acceptor)Pyridinium CompoundsagingkidneyliverNAD(+)nicotinic acid riboside
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.