Evidence map›Paper›PMID 40316694›Full record

ArticleScientific reports2025

Nonlinear association between body roundness index and metabolic dysfunction associated steatotic liver disease in nondiabetic Japanese adults.

Cheng Huang, Zhichao Gao, Zhenxia Huang, Junfeng Xu

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cheng HuangDepartment of Colorectal Surgery, First People's Hospital of Xiaoshan District, Hangzhou, 311200, Zhejiang, China.
Zhichao GaoDepartment of Neurosurgery, First People's Hospital of Xiaoshan District, Hangzhou, 311200, Zhejiang, China.
Zhenxia HuangDepartment of Infectious Diseases, First People's Hospital of Xiaoshan District, Hangzhou, 311200, Zhejiang, China.
Junfeng XuDepartment of Colorectal Surgery, First People's Hospital of Xiaoshan District, Hangzhou, 311200, Zhejiang, China. Xiaoshanyidoctorxu@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global rise in obesity and diabetes has been paralleled by a rising incidence of metabolic dysfunction-associated steatotic liver disease (MASLD). Although previous studies have explored the association between body roundness index (BRI) and MASLD, the specific relationship in non-diabetic Japanese adults requires further investigation. This study analyzed data from 15,299 participants enrolled in the NAGALA cohort (2004-2015) to explore the association between BRI and MASLD through multivariable logistic regression, stratified analysis, and restricted cubic spline modeling. The prevalence of MASLD was 14.46%, with 13.73% occurring in non-obese individuals (BMI < 30). After adjusting for all confounding factors, BRI demonstrated a significant association with MASLD, yielding an adjusted odds ratio of 1.72 (95% CI 1.48-1.99). The restricted cubic spline model revealed a nonlinear relationship, with an inflection point at 3.06. Stratified analyses revealed stronger associations in individuals with lower BMI (≤ 24 kg/m

Indexed as

Fatty LiverAdultAgedBody Mass IndexEast Asian PeopleFemaleHumansJapanMaleMiddle AgedObesityPrevalenceRisk FactorsBody roundness index (BRI)Metabolic dysfunction associated steatotic liver disease (MASLD)Non-diabetic JapaneseNonlinearObesity

Identifiers

PMID40316694
PMCPMC12048529

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.