Evidence map›Paper›PMID 40319270›Full record

Trial reportBMC geriatrics2025

Changes in older persons' lifestyle and perceived health over time and during the COVID-19 pandemic: findings from the extended follow-up of the FINGER randomized controlled trial from 2009 to 2020.

Jenni Lehtisalo, Maria Sääskilahti, Tommi Härkänen, Jenni Kulmala, Katri Hemiö, Sini Siltanen, Zhou Zhi, Francesca Mangialasche, Tiina Laatikainen, Timo Strandberg and 5 more

Registry-linked trialAbstract readRandomized Controlled TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01041989 (Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01041989 naunknown statusnot on this map

Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability

TypeinterventionalSponsorFinnish Institute for Health and WelfareRan2009 to 2025Enrolled1,200ConditionsCognitive Impairment, DementiaArmsNutritional guidance, Exercise, Cognitive training, Reduction of vascular risk factors
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jenni LehtisaloDepartment of Public Health, Lifestyles and Living Environments, Finnish Institute for Health and Welfare, Helsinki, 00271, Finland. jenni.lehtisalo@thl.fi.
Maria SääskilahtiDepartment of Public Health, Lifestyles and Living Environments, Finnish Institute for Health and Welfare, Helsinki, 00271, Finland.
Tommi HärkänenDepartment of Public Health, Lifestyles and Living Environments, Finnish Institute for Health and Welfare, Helsinki, 00271, Finland.
Jenni KulmalaDepartment of Public Health, Lifestyles and Living Environments, Finnish Institute for Health and Welfare, Helsinki, 00271, Finland.
Katri HemiöDepartment of Public Health, Lifestyles and Living Environments, Finnish Institute for Health and Welfare, Helsinki, 00271, Finland.
Sini SiltanenDepartment of Public Health, Lifestyles and Living Environments, Finnish Institute for Health and Welfare, Helsinki, 00271, Finland.
Zhou ZhiDepartment of Public Health, Lifestyles and Living Environments, Finnish Institute for Health and Welfare, Helsinki, 00271, Finland.
Francesca MangialascheDivision of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, Stockholm, 171 64, Sweden.
Tiina LaatikainenDepartment of Public Health, Lifestyles and Living Environments, Finnish Institute for Health and Welfare, Helsinki, 00271, Finland.
Timo StrandbergUniversity of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Riitta AntikainenResearch Unit of Population Health/Geriatrics, University of Oulu, Oulu, FI-90014, Finland.
Jaakko TuomilehtoDepartment of Public Health, Lifestyles and Living Environments, Finnish Institute for Health and Welfare, Helsinki, 00271, Finland.
Hilkka SoininenDepartment of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, 70211, Finland.
Miia KivipeltoDepartment of Public Health, Lifestyles and Living Environments, Finnish Institute for Health and Welfare, Helsinki, 00271, Finland.
Tiia NganduDepartment of Public Health, Lifestyles and Living Environments, Finnish Institute for Health and Welfare, Helsinki, 00271, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultidomain lifestyle trials have been shown to be effective in changing people's behaviour during the intervention, but less is known about long-term effects of such interventions. The aim of this study was to investigate how self-reported lifestyle and self-evaluated health changed over a 10-year period in older adults participating in the FINGER randomised controlled trial. Effects of the initial lifestyle intervention and the COVID-19 pandemic on these behaviour changes were evaluated.

methodsA two-year multicentre FINGER trial recruited community-dwelling people aged 60-77 years at risk of cognitive impairment (n=1259). Participants were randomised to a multidomain lifestyle intervention or regular health advice (control). They underwent study visits annually during the original trial period (at baseline, one, and two years) and twice during the follow-up (five and seven years), and responded to a survey during the COVID-19 pandemic at approximately 10 years. Generalised estimating equations (GEE) and linear mixed-effects regression model were used to analyse physical, cognitive, and social activity, food consumption, smoking, alcohol consumption, and self-evaluated health.

resultsPeople in the intervention group were better able to maintain their level of physical activity up to the five-year follow-up. The intervention group also improved their diet quality: difference in fish consumption was maintained up to the seventh year, and consumption of vegetables and fruits increased during the active intervention. Cognitive and social activities increased and self-evaluated health and memory improved during the active period, but decreased thereafter, without a group difference. During the COVID-19 pandemic, physical and cognitive activities increased.

conclusionMultidomain lifestyle intervention was beneficial for improving physical activity and healthy food choices in older people both in the short and long term, but had no effect on other activities, smoking, alcohol use, or self-evaluated health. Increased physical activity was the most evident pandemic-associated change in older adults' lifestyle.

trial registrationClinicalTrials.gov, NCT01041989. Registered 04/01/2010 - Retrospectively registered, https://clinicaltrials.gov/ .

Indexed as

COVID-19Life StyleAgedExerciseFemaleFollow-Up StudiesHealth BehaviorHumansMaleMiddle AgedPandemicsSARS-CoV-2ChangeCovid-19 pandemicFollow-upInterventionLifestyle

Identifiers

PMID40319270
PMCPMC12048948

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.