Evidence map›Paper›PMID 40321757›Full record

ArticleResearch square2025

Effect of controlled human Plasmodium falciparum infection on B cell subsets in individuals with different levels of malaria immunity.

Pilar Requena, Gloria Patricia Gómez-Pérez, Matthew B B McCall, Diana Barrios, Ruth Aguilar, Julia Fernández-Morata, Marta Vidal, Joseph J Campo, Carla Sanchez, Maria Yazdabankhsh and 7 more

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Pilar RequenaUniversidad de Granada.
Gloria Patricia Gómez-PérezISGlobal.
Matthew B B McCallErasmus MC.
Diana BarriosISGlobal.
Ruth AguilarISGlobal.
Julia Fernández-MorataISGlobal.
Marta VidalISGlobal.
Joseph J CampoAntigen Discovery (United States).
Carla SanchezISGlobal.
Maria YazdabankhshLeiden University Center for Infectious Diseases (LUCID), Leiden University Medical Center.
B Kim Lee SimSanaria Inc.
Stephen L HoffmanSanaria Inc.
Peter KremsnerCentre de Recherches Médicales de Lambaréné (CERMEL).
Bertrand LellCentre de Recherches Médicales de Lambaréné (CERMEL).
Benjamin MordmüllerRadboud University Medical Center.
Carlota DobañoISGlobal.
Gemma MoncunillISGlobal.

Funding

Baseline host and environmental factors that impact pre-erythrocytic malaria vaccine (hypo)responsiveness in endemic regionsU01AI165745 · NIAID · LEIDEN UNIVERSITY MEDICAL CENTER · PI Maria Yazdanbakhsh · 2022 to 2026
$3.3M
Understanding RTS,S malaria vaccine-induced protection through integrated analysiR01AI095789 · NIAID · BARCELONA INTERNATIONAL HEALTH RES CTR · PI DOBANO, CARLOTA · 2012 to 2016
$3.2M
NIAID NIH HHS R01 AI095789NIAID NIH HHS U01 AI165745
6 · The paper itself

Abstract

Continuous exposure to

Indexed as

B cellsControlled human malaria infectioncytokinesPlasmodium falciparum

Identifiers

PMID40321757
PMCPMC12048015

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.