Evidence map›Paper›PMID 40321779›Full record

ArticleResearch square2025

Association between Salivary Immune Markers and Oral Health Conditions in Pregnant Women.

Nora Alomeir, Xinyue Mao, Ruqian Yang, Nasser Assery, Sally Quataert, Antti Seppo, Xingyi Lu, Tong Tong Wu, Jin Xiao

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PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Nora AlomeirEastman Institute for Oral Health.
Xinyue MaoUniversity of Rochester Medical Center.
Ruqian YangEastman Institute for Oral Health.
Nasser AsseryEastman Institute for Oral Health.
Sally QuataertUniversity of Rochester Medical Center.
Antti SeppoUniversity of Rochester Medical Center.
Xingyi LuEastman Institute for Oral Health.
Tong Tong WuUniversity of Rochester Medical Center.
Jin XiaoEastman Institute for Oral Health.

Funding

Understand biological factors underlying early childhood caries disparity from the oral microbiome in early infancyR01DE031025 · NIDCR · UNIVERSITY OF ROCHESTER · PI STEVEN R. GILL, Tongtong Wu · 2022 to 2026
$3.9M
NIDCR NIH HHS R01 DE031025
6 · The paper itself

Abstract

Objectives: This study aims to assess levels of salivary immune markers in women during the 3rd trimester of pregnancy and explores the association between immune markers and dental caries, as well as oral carriage of oral pathogens Methods: Pregnant women from underserved background participated in this study (n = 181). Participants received a comprehensive oral examination by trained and calibrated dentists. Levels of 36 immune markers in unstimulated saliva samples were measured using Bio-Plex200 (Luminex). Salivary Results: The study found high quantities of salivary immune markers in pregnant women with varying detection rates. Univariate analysis found a higher salivary level of IFN-g and TNF-b among women with < 4 decayed teeth, compared to those with ≥ 4 decayed teeth (p < 0.05). Among women with more than 10

Indexed as

Candida albicansCandidiasisCariesImmunityPregnancyStreptococcus mutans

Identifiers

PMID40321779
PMCPMC12047971

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.