Direct Amoxicillin Challenges for Penicillin Allergy Through Pediatric Primary Care Group Visits: A Pilot Study.

Timothy G Chow, Candice Mercadel, Kristin S Alvarez, Madeline Kellam, David A Khan, Cesar Termulo

Abstract read

In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Timothy G ChowDivision of Allergy and Immunology, Departments of Pediatrics and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID https://orcid.org/0000-0002-9999-1275

Candice MercadelCenter of Innovation and Value at Parkland, Parkland Health, Dallas, Texas, USA.ORCID https://orcid.org/0009-0000-5589-2155

Kristin S AlvarezCenter of Innovation and Value at Parkland, Parkland Health, Dallas, Texas, USA.

Madeline KellamDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID https://orcid.org/0000-0002-9589-4638

David A KhanDivision of Allergy and Immunology, Departments of Pediatrics and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Cesar TermuloPopulation Health, Parkland Health, Dallas, Texas, USA.ORCID https://orcid.org/0009-0003-5759-150X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel strategies are needed to expand equitable access to penicillin allergy testing. We performed a pilot study of penicillin allergy testing through direct challenges performed at pediatric primary care group office visits. Ninety-five percent of subjects were delabeled with no severe reactions noted, providing conceptual basis for further implementation studies.

Indexed as

delabelingdrug challengeinfectious diseasepenicillin allergyprimary care

Identifiers

PMID40322269

DOI10.1093/ofid/ofaf236

PMCPMC12048795

What Socratic holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.