Evidence map›Paper›PMID 40322507›Full record

ReviewClinical, cosmetic and investigational dermatology2025

Nail Abnormalities in Scabies Patients: A Systematic Review.

Hendra Gunawan, Risa Miliawati Nurul Hidayah, Pati Aji Achdiat, Retno Hesty Maharani, Fitri Yulianti

Abstract readReview
In one paragraph

Review in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hendra GunawanDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.ORCID 0000-0002-6924-0833
Risa Miliawati Nurul HidayahDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.ORCID 0000-0002-1721-3112
Pati Aji AchdiatDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.ORCID 0000-0002-3010-5052
Retno Hesty MaharaniDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.ORCID 0009-0001-9176-4844
Fitri YuliantiDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Nail abnormalities can be found in patients with scabies. It is commonly misdiagnosed as onychomycosis, traumatic nail disease, or nail psoriasis. Nail changes in patients with scabies are a result of the mites burrowing activity into the stratum corneum of the epidermis, which can extend to the subungual skin of the nail. There are limited studies that have been reported regarding the incidence of nail changes in patients with scabies. Objective: To systematically review nail abnormalities in patients with scabies reported in the literature. Methods: We searched all published articles in electronic databases until August 2024 reporting patients with scabies with detailed descriptions of malformed/diseased nails using specific terms and inclusion/exclusion criteria. This systematic review presents the data as a descriptive analysis. Results: We included 32 articles reporting 33 individual patients with nail scabies. There was no significant difference in the number of scabies patients with nail abnormalities in the children (33.33%), adults (30.30%), and elderly groups (36.36%). The youngest age recorded was four months and the oldest of 92 years. Scabies were more frequent in males (60.61%). According to scabies type, 81.82% of cases of scabies with nail abnormality were crusted scabies. The most prevalent diagnosis approach was direct microscopy (84.84%), followed by histopathological examination (30.30%) and dermoscopy (12.12%). Subungual hyperkeratosis (60.60%), onychodystrophy (48.48%), discoloration (33.33%), and onycholysis (21.21%) constituted the majority of nail abnormalities. Fingernail involvement occurred in 33.33% of the patients, while combined fingernail and toenail involvement occurred in 30.30% of the patients. Conclusion: Subungual hyperkeratosis, onychodystrophy, and discoloration are the most frequent nail abnormalities found in patients with scabies. In order to provide scabies patients with adequate treatment, regular nail examinations should be performed, and further prospective studies are required to completely understand the association between risk factors and abnormalities of the nail in scabies patients.

Indexed as

classic scabiescrusted scabiesnail abnormalitiesscabies

Identifiers

PMID40322507
PMCPMC12049680

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.