Evidence map›Paper›PMID 40322717›Full record

ArticleJournal of clinical medicine research2025

Phenotypic Variability and Hematological Characterization of β

Ahmad Al Tibi, Diya Hasan, Ola M Al-Sanabra, Ghaith H Mansour, Maissa T Shawagfeh, Moath Alqaraleh, Tareq Nayef AlRamadneh, Mutaz Jamal Al-Khreisat, George J Burghel, Amid Abdelnour

Abstract read
In one paragraph

Article in Journal of clinical medicine research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ahmad Al TibiBiolab Diagnostic Laboratories, Amman, Jordan.
Diya HasanDepartment of Allied Medical Sciences, Zarqa College, Al-Balqa Applied University, Zarqa, Jordan.ORCID https://orcid.org/0000-0003-3675-2290
Ola M Al-SanabraDepartment of Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Al-Balqa Applied University, Al-Salt 19117, Jordan.
Ghaith H MansourDepartment of Allied Medical Sciences, Zarqa College, Al-Balqa Applied University, Zarqa, Jordan.
Maissa T ShawagfehDepartment of Allied Medical Sciences, Zarqa College, Al-Balqa Applied University, Zarqa, Jordan.
Moath AlqaralehDepartment of Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Al-Balqa Applied University, Al-Salt 19117, Jordan.
Tareq Nayef AlRamadnehDepartment of Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Zarqa University, Al-Zarqa 13132, Jordan.
Mutaz Jamal Al-KhreisatDepartment of Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Al-Ahliyya Amman University, Amman 19328, Jordan.
George J BurghelManchester Centre for Genomic Medicine and NW Laboratory Genetics Hub, Manchester University Hospitals NHS Foundation Trust, Manchester, UK.
Amid AbdelnourBiolab Diagnostic Laboratories, Amman, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: β-Thalassemia is a genetic disorder characterized by decreased or completely absent β-globin synthesis, leading to a spectrum of clinical manifestations. It is a major public health concern in Jordan, as in other Mediterranean countries. β-Thalassemia carriers are normally asymptomatic; nevertheless, laboratory examinations often reveal mild anemia characterized by microcytic hypochromic erythrocytes, with differences influenced by specific phenotypes. This study aimed to assess and correlate the variants among β Methods: One hundred forty-five β-thalassemia carriers were recruited from various governorates in Jordan. Hematological parameters, including complete blood count (CBC) and capillary electrophoresis of hemoglobin (Hb), were evaluated in all participants. Molecular techniques, specifically polymerase chain reaction (PCR) with hybridization, were employed to identify β-thalassemia variants and classify the participants as having β Results: Among the 145 β-thalassemia carriers, 64 (44.14%) and 81 (55.86%) had β Conclusions: Hb, MCV, MCH, and Hb-A

Indexed as

HemoglobinopathiesHemoglobin variantsPathogenic variantsPhenotypeβ-thalassemia

Identifiers

PMID40322717
PMCPMC12045796

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.