Evidence mapPaperPMID 40322997Full record

ArticleHaemophilia : the official journal of the World Federation of Hemophilia2025

Outcomes of Dental Treatment Procedures in People With Haemophilia Treated Under a Comprehensive Care Model: An Analysis of Cases From a Tertiary Care Centre.

Mathangi Kumar, Sulochana Badagabettu, Keerthilatha M Pai, Annamma Kurien, Archana Mv, Shreemathi S Mayya, Sreejith Govindan

Abstract read
In one paragraph

Article in Haemophilia : the official journal of the World Federation of Hemophilia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mathangi KumarDepartment of Oral Medicine & Radiology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.ORCID https://orcid.org/0000-0003-1245-2314
Sulochana BadagabettuDepartment of Fundamentals of Nursing, Manipal College of Nursing, Manipal Academy of Higher Education, Manipal, Karnataka, India.ORCID https://orcid.org/0000-0002-2242-3413
Keerthilatha M PaiDepartment of Dental Surgery, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India.ORCID https://orcid.org/0000-0003-0967-5867
Annamma KurienManipal University College Malaysia, Bukit Baru, Melaka, Malaysia.ORCID https://orcid.org/0000-0003-4986-9893
Archana MvDepartment of Pediatric Hemato-Oncology, Kasturba Medical College and Hospital, Manipal Academy of Higher Education, Manipal, Karnataka, India.ORCID https://orcid.org/0000-0002-7616-6408
Shreemathi S MayyaDepartment of Data Science, Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, Karnataka, India.ORCID https://orcid.org/0000-0003-0753-9490
Sreejith GovindanDepartment of Basic Medical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.ORCID https://orcid.org/0000-0002-2984-5053

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHaemophilia is a chronic, lifelong bleeding disorder that requires interdisciplinary care to manage and mitigate the disease burden throughout a patient's life. There is no universally accepted protocol for managing haemophilia patients during dental care.

objectiveTo evaluate the state of practice employed for people with haemophilia undergoing various dental treatment procedures under a comprehensive care model in a tertiary care setting.

methodsPatient records from the archives of Haemophilia Society of Kasturba Hospital, Manipal were retrieved, and the demographic data, disease status and dental treatment records of each patient were systematically reviewed. The various dental procedures and the outcomes were correlated with the severity of haemophilia and the quantity of prophylactic factors concentrate utilised for the dental treatment procedures.

resultsA total of 73 patients attended the comprehensive Haemophilia clinic during the study period. Sixty nine of them underwent 84 dental treatment procedures. The various dental procedures that were performed on these patients were oral prophylaxis (scaling), extraction of grossly decayed teeth, restoration (fillings) of carious teeth, endodontic treatment and other minor oral surgical procedures. The amount of clotting factor concentrates given prior to dental treatment ranged from 250 to 1500 IU. None of the patients had excessive haemorrhage following dental procedures. Statistical analyses were performed with SPSS software, and statistical significance was set at p < 0.05. Chi-square and Fisher's exact test were used for the analysis of quantitative variables.

conclusionStandardisation of prophylactic clotting factors for various dental treatment procedures is essential to prevent haemorrhagic complications.

trial registrationClinical Trials Registry - India (CTRI) number: REF/2024/01/077096.

Indexed as

Comprehensive Health CareDental CareHemophilia AAdolescentAdultChildFemaleHumansMaleMiddle AgedTertiary Care CentersTreatment OutcomeYoung Adultdental treatmenthaemophiliaoral healthoutcomes

Identifiers

PMID40322997
PMCPMC12306850

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.