Evidence map›Paper›PMID 40323239›Full record

ArticleGut microbes2025

Defining enteric bacterial pathogenesis using organoids:

Yan Chen, Ashley Gilliland, Qiaochu Liang, Xiao Han, Hyungjun Yang, Jocelyn Chan, Dominique Lévesque, Kyung-Mee Moon, Parandis Daneshgar, François-Michel Boisvert and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The growth and pathogenesis ofInfection and immunity · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yan ChenDivision of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.ORCID 0009-0006-8223-4864
Ashley GillilandDivision of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0003-0616-0956
Qiaochu LiangDivision of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0002-8407-1708
Xiao HanDivision of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Hyungjun YangDivision of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0002-3213-7568
Jocelyn ChanDivision of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Dominique LévesqueDepartment of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, Canada.
Kyung-Mee MoonDepartment of Biochemistry and Molecular Biology, Michael Smith Laboratories, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
Parandis DaneshgarDepartment of Chemistry, University of British Columbia, Kelowna, BC, Canada.
François-Michel BoisvertDepartment of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, Canada.ORCID 0000-0001-8882-8619
Leonard FosterDepartment of Biochemistry and Molecular Biology, Michael Smith Laboratories, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0001-8551-4817
Wesley F ZandbergDepartment of Chemistry, University of British Columbia, Kelowna, BC, Canada.
Kirk BergstromDepartment of Biology, University of British Columbia, Kelowna, BC, Canada.ORCID 0000-0002-0747-9566
Hong B YuDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas, USA.ORCID 0000-0002-3351-322X
Bruce A VallanceDivision of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0003-1345-6747

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enteric bacterial pathogens pose significant threats to human health; however, the mechanisms by which they infect the mammalian gut in the face of daunting host defenses remain to be fully defined. For the attaching and effacing (A/E) bacterial family member and murine pathogen

Indexed as

Bacterial ProteinsCitrobacter rodentiumColonEnterobacteriaceae InfectionsIntestinal MucosaMucusOrganoidsAnimalsMiceMice, Inbred C57BLVirulenceBacterial Proteinsair-liquid interfacecolonoidsEnteric pathogensEspCmucus

Identifiers

PMID40323239
PMCPMC12054374

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.