Evidence mapPaperPMID 40323472Full record

ArticleJournal of cancer research and clinical oncology2025

The status and determinants of demoralization in patients with colorectal cancer: a cross-sectional study in China.

Dan Zhou, Fanfan Shi, Jie Yang, Lili Jiang, Luo Yang, Jin Wen

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Article in Journal of cancer research and clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Dan Zhou *Colorectal Cancer Center Ward, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Fanfan Shi *Department of Clinical Research and Management, Center of Biostatistics, Design, Measurement and Evaluation (CBDME), West China Hospital, Sichuan University, Chengdu, China.
Jie YangColorectal Cancer Center Ward, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Lili JiangColorectal Cancer Center Ward, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Luo YangHemodialysis Center, Department of Nephrology, West China Hospital, Sichuan University, Chengdu, China.
Jin WenInstitute of Hospital Management, West China Hospital, Sichuan University, Chengdu, Sichuan, China. huaxiwenjin@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the occurrence and severity of demoralization syndrome (DS) in colorectal cancer (CRC) patients in China, and explore its influencing factors, so as to provide evidence for the formulation of psychological care strategies for colorectal cancer patients.

methodsThis study was a cross-sectional design. A questionnaire was formulated to investigate the demographic, disease characteristics and treatment information, demoralization syndrome, social support, anxiety and depression of patients, who treated in Colorectal Cancer Center of West China Hospital of Sichuan University from May to July 2023. t test, Wilcoxon rank sum test, Chi-square test or Fisher exact probability method were used for univariate analysis, and binary logistic regression analysis was used to explore the factors affecting demoralization syndrome.

results445 colorectal cancer patients participated in this study, and the median score of demoralization syndrome was 10 (5-14), showing moderate demoralization syndrome. Univariate analysis showed that gender, tumor metastasis, social support, anxiety and depression might related to the severity of demoralization syndrome. Binary logistic regression showed, patients without tumor metastasis had a lower risk of developing moderate-to-severe demoralization syndrome compared with patients with tumor metastasis (OR = 0.522, 95%CI 0.319 ~ 0.848). The higher the anxiety and depression score, the higher the risk of moderate to severe demoralization syndrome (OR = 1.490, 95%CI 1.349 ~ 1.657, and OR = 1.167, 95%CI 1.073 ~ 1.272), P < 0.001.

conclusionsIt is necessary to consider the disease characteristics of colorectal cancer patients and the impact of treatment on patients to develop psychological nursing strategies comprehensively.

Indexed as

Colorectal NeoplasmsAdultAgedAnxietyChinaCross-Sectional StudiesDepressionFemaleHumansMaleMiddle AgedSocial SupportSurveys and QuestionnairesAnxietyCancer metastasisColorectal cancerDemoralization syndromeDepression

Identifiers

PMID40323472
PMCPMC12053192

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.