Evidence map›Paper›PMID 40323735›Full record

ArticleEpilepsia open2025

Knowledge, attitudes, and practices of epilepsy patients regarding the ketogenic diet therapy: A cross-sectional study.

Xiuping Zhang, Meizhen Sun, Guofang Xue, Yongxiong Zhao, Taotao Du, Xueying Guan, Yong Xu

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Article in Epilepsia open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Xiuping ZhangThe Second Hospital of Shanxi Medical University, Taiyuan, China.
Meizhen SunThe First Hospital of Shanxi Medical University, Taiyuan, China.
Guofang XueThe Second Hospital of Shanxi Medical University, Taiyuan, China.
Yongxiong ZhaoThe Second Hospital of Shanxi Medical University, Taiyuan, China.
Taotao DuFenyang Hospital of Shanxi Province, Fenyang, China.
Xueying GuanShanxi Medical University, Taiyuan, China.
Yong XuShanxi Medical University, Taiyuan, China.ORCID https://orcid.org/0000-0001-9679-2273

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe therapeutic ketogenic diet is typically used in epilepsy treatments, yet there has been insufficient understanding regarding the knowledge, attitudes, and practices (KAP) of epilepsy patients concerning this dietary therapy. This study aims to investigate the KAP of epilepsy patients regarding ketogenic diet therapy, with the goal of identifying gaps in knowledge and attitudes that may impact clinical outcomes.

methodA cross-sectional study was conducted between November 2023 and December 2023 at three epilepsy centers in Shanxi Province: the First Hospital of Shanxi Medical University, the Second Hospital of Shanxi Medical University, and Taiyuan Epilepsy Hospital. Data, including demographic characteristics and KAP scores, were collected via online questionnaires, yielding a total of 612 valid responses, with 320 (52.29%) males.

resultsThe mean KAP scores were calculated as follows: knowledge score 4.99 ± 6.72 (possible range: 0-24), attitude score 24.82 ± 2.34 (possible range: 8-40), and practice score 29.48 ± 8.49 (possible range: 9-45). Multivariate analysis revealed that the attitude score (OR = 1.443, 95% CI: [1.296-1.607], p < 0.001) and an epilepsy duration of 5-10 years (OR = 3.086, 95% CI: [1.716-5.548], p < 0.001) were independently associated with positive practice. Additionally, Structural Equation Modeling indicated that knowledge (β = 0.034, p = 0.012) and attitude (β = 0.583, p = 0.010) directly influenced practice, while knowledge also directly affected attitude (β = 0.565, p = 0.013), with an indirect effect on practice through attitude (β = 0.329, p = 0.009). SIGNIFICANCE: The study found insufficient knowledge, suboptimal attitudes, and negative practices toward the ketogenic diet among epilepsy patients. This underscores the need for targeted educational interventions to enhance patient engagement and optimize clinical outcomes. PLAIN LANGUAGE SUMMARY: This study looked at how much epilepsy patients know about, feel about, and use the ketogenic diet as a treatment. We found that patients generally know little about the diet, have mixed feelings, and do not use it much. Better understanding and positive attitudes were linked to better use of the diet. The results suggest that more education could help patients use the diet more effectively, which might improve their health outcomes.

Indexed as

Diet, KetogenicEpilepsyHealth Knowledge, Attitudes, PracticeAdolescentAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedSurveys and QuestionnairesYoung Adultattitudesepilepsyketogenic dietknowledgepractices

Identifiers

PMID40323735
PMCPMC12163517

What Socratic holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.