Evidence map›Paper›PMID 40323931›Full record

ArticleAmerican journal of reproductive immunology (New York, N.Y. : 1989)2025

Initial and Longitudinal Trajectories in Hemoglobin Levels Predict the Prognosis of Patients With Premature Rupture of Membranes.

Ying-Ying Chen, Hai-Xing Huang, Min Xiao

Abstract read
In one paragraph

Article in American journal of reproductive immunology (New York, N.Y. : 1989), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Ying-Ying ChenDepartment of Obstetrics and Gynecology, Hangzhou Linping District Maternal & Child Health Care Hospital, Hangzhou, Zhejiang, China.
Hai-Xing HuangDepartment of Obstetrics and Gynecology, Hangzhou Linping District Maternal & Child Health Care Hospital, Hangzhou, Zhejiang, China.
Min XiaoDepartment of Obstetrics and Gynecology, Hangzhou Linping District Maternal & Child Health Care Hospital, Hangzhou, Zhejiang, China.ORCID 0000-0002-5515-7596

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

problemPremature rupture of membranes (PROM) can lead to adverse maternal and neonatal outcomes. Identifying predictors of length of hospital stay (LOS) in PROM patients can aid in improving management and prognosis. METHOD OF STUDY: The Medical Information Mart for Intensive Care IV database was searched to acquire data on PROM individuals. A univariable analysis, LASSO regression, and multivariable generalized linear model (GLM) were adopted to identify factors closely related to LOS. Next, the change trends in the key variable over multiple time points were determined using a latent class trajectory model (LCTM). The association of these trajectories with LOS was analyzed using GLMs.

resultsThe retrospective study finally enrolled 868 samples. The significant factors included initial hemoglobin, chorioamnionitis, premature birth, and rupture to delivery interval <24 h. Notably, higher initial hemoglobin level was independently associated with shorter LOS (β = -0.599; 95% CI = [-0.846, -0.352]; p < 0.05). The stratified analysis confirmed this association in all subgroups except those with chorioamnionitis. The LCTM identified three hemoglobin trajectories. Compared to other trajectory groups, the "lowest, declining" group had longer LOS (p < 0.05).

conclusionsPROM patients with lower initial hemoglobin levels and the "lowest, declining" trajectory group were linked to longer LOS. Monitoring and managing hemoglobin levels is important in improving patient outcomes.

Indexed as

HemoglobinsPremature Rupture of Fetal MembranesAdultChorioamnionitisFemaleHumansInfant, NewbornLength of StayLongitudinal StudiesPregnancyPremature BirthPrognosisRetrospective StudiesHemoglobinsinitial hemoglobinlength of hospital staypremature rupture of membranesprognosistrajectory of hemoglobin level

Identifiers

PMID40323931
PMCPMC12052199

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.