Evidence map›Paper›PMID 40323986›Full record

ArticlePLOS global public health2025

Organization of services for severe chronic Noncommunicable diseases at first-level hospitals in nine lower-income countries: Results from a Baseline assessment of PEN-Plus initiation.

Chantelle Boudreaux, Emily B Wroe, Ada Thapa, Natnael A Abebe, Ann R Akiteng, Laura Drown, Abhijit Gadewar, Biraj M Karmacharya, Sandeepa Karki, Maryam Mansoor and 10 more

Abstract read
In one paragraph

Article in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Chantelle BoudreauxDivision of Global Health Equity, Center for Integration Science in Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.ORCID https://orcid.org/0000-0001-9776-8523
Emily B WroeDivision of Global Health Equity, Center for Integration Science in Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
Ada ThapaDivision of Global Health Equity, Center for Integration Science in Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.ORCID https://orcid.org/0009-0004-4210-6265
Natnael A AbebeDivision of Global Health Equity, Center for Integration Science in Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.ORCID https://orcid.org/0000-0001-7221-6378
Ann R AkitengUganda, Initiative for Integrated Management of Non communicable Diseases (UINCD), Kampala, Uganda.
Laura DrownDivision of Global Health Equity, Center for Integration Science in Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
Abhijit GadewarSangwari - People's Association for Equity and Health, Ambikapur, Chhattisgarh, India.
Biraj M KarmacharyaDhulikhel Hospital, Kathmandu University School of Medical Sciences, Dhulikhel, Nepal.
Sandeepa KarkiKathmandu Institute of Child Health (KIOCH), Kathmandu, Nepal.
Maryam MansoorDivision of Global Health Equity, Center for Integration Science in Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
Reuben MutagaywaMuhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.ORCID https://orcid.org/0000-0002-0928-8149
Bavin MulengaCentre for Infectious Diseases Research in Zambia, Lusaka, Zambia.
Alvern MutengerereSolidarMed, Masvingo, Zimbabwe.
Laura NollinoDepartment of Medicine, Endocrine Metabolism and Nutrition Diseases Unit, AULSS 2 Marca Trevigiana, Treviso, Italy.ORCID https://orcid.org/0000-0001-9770-5629
Devashri SalviDivision of Global Health Equity, Center for Integration Science in Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
Wubaye Walelgne DagnawDivision of Global Health Equity, Center for Integration Science in Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
Gene BukhmanDivision of Global Health Equity, Center for Integration Science in Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
Ana O MocumbiUniversidade Eduardo Mondlane, Campus Universitário, Maputo, Mozambique.
Alma AdlerDivision of Global Health Equity, Center for Integration Science in Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
PEN-Plus working group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe chronic noncommunicable diseases pose a significant health burden and challenges for health systems globally. This study aims to advance our understanding of the current organization of care for these conditions in low and lower-middle-income countries. The study was conducted as part of a baseline assessment of facilities prior to the initiation of the Package of Essential NCD Interventions -Plus (PEN-Plus) strategy, which is designed to enhance outpatient care for conditions including rheumatic and congenital heart disease, sickle cell disease, type 1 diabetes, severe asthma, and advanced chronic kidney disease. We employed a cross-sectional survey methodology to collect baseline data from 16 hospitals in nine LLMICs. The survey assessed the organization of common and severe NCD services, focusing on the availability and management of severe NCDs, organized into domains of integrated services. Data were analyzed using summary statistics and heatmaps to evaluate care patterns. We document gaps in the availability of services for both common and severe NCDs. We find that the majority of NCD care occurs in the general outpatient settings, with a smaller proportion provided in specialized internal medicine wards. Despite some hospitals implementing specialized clinics and teams, limitations in specialist access, variability in service fees, and inconsistent definitions of patient follow-up were prominent issues affecting patient care access and continuity. Despite the spectrum of strategies employed by these hospitals to cater to chronically and severely ill patients, notable gaps in care persist, particularly for diagnostic and treatment options that require specialist training or equipment. The sustainable decentralization of effective care for individuals with severe chronic NCDs will require integrated teams and customized systems to ensure seamless and comprehensive care through the entire care continuum-from screening and diagnosis to care linkage, ongoing management, handling of complications, uninterrupted supply of medicines and commodities and maintaining patient retention.

Identifiers

PMID40323986
PMCPMC12052158

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.