Evidence map›Paper›PMID 40324014›Full record

SynthesisVeterinary medicine and science2025

Anaplasma Phagocytophilum, a Zoonotic Vector-Borne Bacterial Species in Rodents and Its Associated Tick Vector: Systematic Review.

Maropeng C Monyama, Tsepo Ramatla, Bradly Khosa, Tshepo Mafokwane, Oriel Thekisoe

Abstract readSystematic Review
In one paragraph

Synthesis in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Tick-Borne Pathogens in Wild Cervids from Poland: A Molecular Survey onAnimals : an open access journal from MDPI · 2026
    Article
  2. Article
  3. Review
  4. Molecular detection and genetic diversity ofFrontiers in microbiology · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maropeng C MonyamaDepartment of Life and Consumer Sciences, University of South Africa, Florida, South Africa.ORCID 0000-0001-8912-6002
Tsepo RamatlaCentre for Applied Food Safety and Biotechnology, Department of Life Sciences, Central University of Technology, Bloemfontein, South Africa.ORCID 0000-0002-0473-8075
Bradly KhosaDepartment of Life and Consumer Sciences, University of South Africa, Florida, South Africa.
Tshepo MafokwaneDepartment of Life and Consumer Sciences, University of South Africa, Florida, South Africa.
Oriel ThekisoeUnit for Environmental Sciences and Management, North-West University, Potchefstroom, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe bacterium Anaplasma phagocytophilum, the causative agent of tick-borne fever, is alleged to be naturally maintained in a tick-rodent cycle, with human beings involved only as incidental impasse hosts. This study was undertaken to update scientific evidence on the occurrence of A. phagocyphilum in rodents and its associated tick species.

resultsThe systematic review was executed using the PRISMA guidelines to assess and compile the relevant literature. Published journal articles from 1 January 2000 to August 2023 were sourced from three electronic databases, including PubMed, ScienceDirect and Google Scholar, and after evaluation of the articles, ultimately 23 were eligible for this systematic review. Of the eligible studies, 43.5% did not report on the detection of A. phagocytophilum in tick species but only in rodents, whilst 26.1% of the studies, reported on negative detection of A. phagocytophilum in both rodents and ticks. In terms of rodents, there were 11 genera observed from the eligible studies with Apodemus spp. being the most frequently reported host, followed by Microtus spp. and Myodes spp. Ixodes ticks including I. ricinus and I. trianguliceps were the most frequent tick species investigated as arthropod carriers/vectors in the studies, followed by Dermacentor and Haemaphysalis tick species.

conclusionsThis study has consolidated information from published articles on the role that rodents play as hosts or carriers of A. phagocytophilum and the possible role that related tick species play as vectors. Various tick species play a significant role as vectors of Anaplasma phagocytophilum and infect a wide array of rodent hosts that may possibly interact with humans.

Indexed as

Anaplasma phagocytophilumArachnid VectorsEhrlichiosisRodent DiseasesRodentiaAnimalsAnaplasma phagocytophilumrodentstick vector

Identifiers

PMID40324014
PMCPMC12051846

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.