Evidence map›Paper›PMID 40324093›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Exploiting thioether reactivity to label mycobacterial glycans.

Stephanie R Smelyansky, Chi-Wang Ma, Victoria M Marando, Gregory H Babunovic, So Young Lee, Bryan D Bryson, Laura L Kiessling

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stephanie R SmelyanskyDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0009-0004-2930-2907
Chi-Wang MaDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0002-6785-5148
Victoria M MarandoDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0002-3557-5838
Gregory H BabunovicDivision of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA 02115.ORCID 0000-0003-4158-6979
So Young LeeDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0009-0003-2026-496X
Bryan D BrysonRagon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, MA 02139.ORCID 0000-0003-1716-6712
Laura L KiesslingDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0001-6829-1500

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ARTHUR Y KIM · 2004 to 2026
$94.4M
VIRUS PRODUCTION COREP30CA014051 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Jacqueline A. Lees · 1985 to 2026
$93.9M
Study of M. tuberculosis under human host selection to identify virulence and barrier lipids (Project 1)U19AI162584 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MOODY, DAVID BRANCH · 2021 to 2025
$13.5M
The Chemistry and Biology of Galactofuranose-Containing GlycansR01AI126592 · NIAID · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Laura L Kiessling · 2017 to 2026
$5.2M
Chemical Biological Discovery of Lipid Virulence Factors in the Major Bacterial PathogensR01AI165573 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MOODY, DAVID BRANCH · 2022 to 2025
$3.0M
IL-26 in host defense against infection by intracellular bacteria in skinR01AR073252 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MODLIN, ROBERT L · 2019 to 2023
$2.1M
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) Al-126592HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01A1022553HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R1AR073252NCI NIH HHS P30 CA014051NIAID NIH HHS P30 AI060354NIAID NIH HHS R01 AI126592NIAID NIH HHS R01 AI165573NIAID NIH HHS U19 AI162584NIAMS NIH HHS R01 AR073252NSF | EDU | Division of Graduate Education (DGE) GRFP 1745302
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mycobacterium tuberculosisPolysaccharidesSulfidesCell WallHumansLipopolysaccharideslipoarabinomannanLipopolysaccharidesPolysaccharidesSulfidesbioconjugationglycansmannose-capped lipoarabinomannanmycobacteriaMycobacterium tuberculosis

Identifiers

PMID40324093
PMCPMC12088412

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.