Evidence map›Paper›PMID 40324632›Full record

ArticleJournal of advanced research2026

Rab32-based vesicles coordinate mitochondria and actin for spindle migration and organelle rearrangement in oocyte meiosis.

Hao-Lin Zhang, Qian Cui, Xiao-Ting Yu, Yu-Xuan Hou, Rui-Jie Ma, Ping-Shuang Lu, Yue Wang, Shao-Chen Sun, Hong-Hui Wang

Abstract read
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In one paragraph

Article in Journal of advanced research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Effect of Anti-Müllerian Hormone on Oocytes In Vitro Maturation in Sheep.International journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hao-Lin ZhangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Qian CuiCenter of Reproductive Medicine, The Affiliated Weihai Second Municipal Hospital of Qingdao University, Weihai, China.
Xiao-Ting YuCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China; Key Laboratory of Research on Clinical Molecular Diagnosis for High Incidence Diseases in Western Guangxi of Guangxi Higher Education Institutions, Reproductive Medicine of Guangxi Medical and Health Key Discipline Construction Project, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Yu-Xuan HouCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Rui-Jie MaCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Ping-Shuang LuCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Yue WangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Shao-Chen SunCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China; Key Laboratory of Research on Clinical Molecular Diagnosis for High Incidence Diseases in Western Guangxi of Guangxi Higher Education Institutions, Reproductive Medicine of Guangxi Medical and Health Key Discipline Construction Project, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China. Electronic address: sunsc@njau.edu.cn.
Hong-Hui WangCenter of Reproductive Medicine, The Affiliated Weihai Second Municipal Hospital of Qingdao University, Weihai, China. Electronic address: wanghh89@qdu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRab32 is a part of the Rab GTPase family, which is known as the regulator of vesicle transport for an array of cellular functions including endosomal transport, autophagy, generation of melanosomes, phagocytosis and inflammatory processes.

objectiveHowever, the role of Rab32 in oocyte meiosis is still not well-defined.

methodsWe depleted Rab32 expression by knock down approach, and we also disrupted Rab32 function by exogenous Rab32

resultsIn our current investigation, we delved into its impacts on the cytoskeleton dynamics and the functionality of organelles during the meiotic maturation process in mouse oocytes. Rab32 expressed during oocyte meiosis and deletion of Rab32 or the expression of exogenous Rab32

conclusionsIn summary, our study unravels the critical functions of Rab32 for the interplay between actin and mitochondria, which further facilitates movement of the spindle apparatus and organelles arrangement in mouse oocyte meiotic development.

Indexed as

ActinsMeiosisMitochondriaOocytesrab GTP-Binding ProteinsSpindle ApparatusAnimalsAutophagyFemaleMiceActinsrab GTP-Binding ProteinsActinMeiosisMitochondriaOrganellesRab32

Identifiers

PMID40324632
PMCPMC12869199

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.