Evidence map›Paper›PMID 40325244›Full record

SynthesisSurgical endoscopy2025

Long-term changes in lipid indices following Roux-en-Y gastric bypass: a meta-analysis.

Tannaz Jamialahamdi, Elaheh Mirhadi, Mohammed A Abdalla, Kishore M Gadde, Wael Almahmeed, Ali H Eid, Saheem Ahmad, Irfan Ahmad, Matthew Kroh, Amirhossein Sahebkar

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tannaz JamialahamdiPharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Elaheh MirhadiBiotechnology Research Center, School of Pharmacy, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammed A AbdallaDepartment of Translational Research, Dasman Diabetes Institute, Kuwait, State of Kuwait.
Kishore M GaddeDepartment of Surgery, University of California Irvine Medical Center, Orange, CA, USA.
Wael AlmahmeedCleveland Clinic Abu Dhabi, Heart and Vascular Institute, Abu Dhabi, United Arab Emirates.
Ali H EidDepartment of Basic Medical Sciences, College of Medicine, QU Health, Qatar University, Doha, Qatar.
Saheem AhmadDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, University of Hail, 2440, Hail, Saudi Arabia.
Irfan AhmadCentral Labs, King Khalid University, P.O. Box 960, AlQura'a, Abha, Saudi Arabia.
Matthew KrohCleveland Clinic, Digestive Disease and Surgery Institute, Cleveland, OH, USA.
Amirhossein SahebkarBiotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran. amir_saheb2000@yahoo.com.ORCID http://orcid.org/0000-0002-8656-1444

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBariatric surgery yields clinically significant long-term weight loss accompanied by marked improvements in numerous weight-related comorbidities including type 2 diabetes, hypertension, dyslipidemia, obstructive sleep apnea, and fatty liver disease.

objectiveThis systematic review and meta-analysis aimed to evaluate the effect of (RYGB) surgery on lipid profile. DATA SOURCE: We searched PubMed, Scopus, Web of Science and Scholar from inception to May 20th, 2024. STUDIES SELECTION: Clinical studies that reported lipid profile data with a follow-up of at least 5 years after RYGB were eligible. DATA EXTRACTION: Two independent reviewers extracted data and assessed the risk of bias.

resultsOf the 4922 articles identified from our database search, 38 studies that measured lipid profile following RYGB were identified and selected for the analysis. Compared to pre-surgery, at post-surgery follow-up of ≥ 5 years, RYGB was associated with significant reductions in mean total cholesterol (TC) (WMD: - 17.95 mg/dl, 95% CI: - 22.68, - 13.22, 95% PI: - 46.18, 10.27 p < 0.001; I

conclusionRYBG is associated with clinically significant large improvements in serum lipids at a post-operative follow-up of 5 years or more.

Indexed as

Gastric BypassLipidsObesity, MorbidHumansTreatment OutcomeWeight LossLipidsBariatric surgeryLipid profileRoux-en-Y gastric bypass

Identifiers

PMID40325244

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.