Trial reportBMC cardiovascular disorders2025
Using structural equation model to analyse the effect of psychological pressure on the patients with essential hypertension blood pressure and blood biochemical indicators.
Trial report in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Association of cumulative cholesterol-HDL-glucose index with blood pressure changes and risk of new-onset hypertension in middle-aged and older adults: a cohort study.Cardiovascular diabetology · 2026Article
- Prevalence and correlates of perceived stress and psychological health among residents receiving standardized training: a multicenter cross-sectional survey study in China.BMC public health · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEssential hypertension (EH) was the result of the combined action of environmental and genetic factors, and its risk factors were numerous, psychological factors were thought to contribute to the development of EH.
methodsWe randomized 600 outpatients and inpatients during the year from January 2018 to December 2021 in the Ningbo Medical Treatment Center Li Huili Hospital. Basic information including blood pressure, blood lipids, AngII, aldosterone and Homocysteine was recorded, and the Chinese Perceived Stress Scale (CPSS) questionnaire was completed. We divided them into four groups: high psychological pressure hypertension group(HPPH), low psychological pressure hypertension group(LPPH), high psychological pressure control group (HPPC) and low psychological pressure control group (LPPC). Using SEM to explore the direct and indirect effects of psychological pressure on blood pressure and biochemical indicators.
resultSBP, DBP, TC, TG, LDL-C, Ang II, ALD and Hcy of HPPH were significantly higher than those of LPPH, HPPC and LPPC (p < 0.05). SBP, DBP, TC, TG, LDL-C, Ang II, ALD and Hcy of LPPH were significantly higher than those of HPPC and LPPC. SBP, DBP, TC, TG, LDL-C, Ang II, ALD and Hcy of HPPC were significantly higher than those of LPPC. HDL-C were lowest in HPPH group. Psychological pressure had significantly effect on blood pressure, lipids, AngII, ALD and Hcy(P < 0.05), and it had positive relationship with SBP, DBP, TC, TG, HDL-C, Ang II, ALD, Hcy (P < 0.05), and had negative relationship with HDL-C. AngII and ALD had significantly effects on blood pressure, lipids (P < 0.05), and it had positive relationship with SBP, DBP, TC, TG, ALD(P < 0.05), and had negative relationship with HDL-C(P < 0.05). Blood pressure had significantly effects on Lipids and Hcy (P < 0.05), it had positive relationship with TC, TG, LDL-C (P < 0.05), and had negative relationship with HDL-C(P < 0.05).
conclusionThe research demonstrated that psychological pressure plays an important role in the pathophysiological process of essential hypertension and may serve as a potential target for comprehensive hypertension management. CLINICAL TRIAL NUMBER: Not applicable.
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