Evidence map›Paper›PMID 40328676›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2025

Dextran-Assisted Biomimetic Fabrication of CdSe:Eu QDs With Enhanced Biocompatibility and Stability.

Myrto Margariti, Marianna Roussaki, Elias Sakellis, Nikos Boukos, Maria Theodosiou, Nikoleta Kostopoulou, Eleni K Efthimiadou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Myrto MargaritiInorganic Chemistry Laboratory, Department of Chemistry, National and Kapodistrian University of Athens, Zografou, 15771, Greece.
Marianna RoussakiInorganic Chemistry Laboratory, Department of Chemistry, National and Kapodistrian University of Athens, Zografou, 15771, Greece.
Elias SakellisInstitute of Nanoscience and Nanotechnology, National Center of Scientific Research "Demokritos", Agia Paraskevi, 15341, Greece.
Nikos BoukosInstitute of Nanoscience and Nanotechnology, National Center of Scientific Research "Demokritos", Agia Paraskevi, 15341, Greece.
Maria TheodosiouInorganic Chemistry Laboratory, Department of Chemistry, National and Kapodistrian University of Athens, Zografou, 15771, Greece.
Nikoleta KostopoulouInorganic Chemistry Laboratory, Department of Chemistry, National and Kapodistrian University of Athens, Zografou, 15771, Greece.
Eleni K EfthimiadouInorganic Chemistry Laboratory, Department of Chemistry, National and Kapodistrian University of Athens, Zografou, 15771, Greece.ORCID https://orcid.org/0000-0002-6293-7881

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A dextran templated biomimetic synthetic approach was applied for the preparation of Cadmium Selinium:Europium Quantum Dots (CdSe:Eu QDs). The present work examines synthetic variables including the effect of increasing Europium concentration during QDs' synthesis and the use of different coating agents (citrate versus APTES) to improve the QDs' colloidal stability and ameliorate their cytotoxic behavior. All samples were subjected to structural and morphological characterizations via Fourier Transform infrared (FT-IR) spectroscopy, UV-Visible (UV-Vis) spectrophotometry, Transmission Electron Microscopy (TEM), and Dynamic Light Scattering (DLS). Subsequently, biological evaluation of all the synthesized samples of bare and APTES coated CdSe:Eu QDs was conducted on epithelial HaCaT and breast cancer MCF-7. Wound healing assays were conducted to assess cytotoxicity and cell migration under QD treatment. Results showed that both coated and uncoated QDs influenced wound closure rates in a concentration- and time-dependent manner. Finally, fluorescence microscopy revealed significant green luminescence of CdSe:Eu quantum dots (QDs) in both HaCaT and MCF-7 cell lines, indicating efficient cellular uptake. The internalization of QDs was influenced by their surface properties and charge, suggesting an endocytic uptake pathway.

Indexed as

Biocompatible MaterialsBiomimetic MaterialsCadmium CompoundsDextransEuropiumQuantum DotsSelenium CompoundsBiomimeticsCell MovementCell SurvivalHaCaT CellsHumansMCF-7 CellsSpectroscopy, Fourier Transform InfraredBiocompatible MaterialsCadmium Compoundscadmium selenideDextransEuropiumSelenium Compoundsbiological evaluationcadmiumcolloidal solutioneuropiumnanoparticlesnanotechnologyquantum dotsselenium

Identifiers

PMID40328676
PMCPMC12272029

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.