ArticleMicrosystems & nanoengineering2025
Foldable 3D opto-electro array for optogenetic neuromodulation and physiology recording.
Article in Microsystems & nanoengineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Origami and Kirigami on Nanomembranes: Design, Fabrication, and Applications.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Three-dimensional microelectrode arrays forBiomedical engineering letters · 2026Review
- Full-Stack Architectures for Intelligent Brain-Computer Interfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Bridging the Gap: Integrated High-Density Microelectrode Arrays for Cellular, Organoid, and Clinical Electrophysiology.Micromachines · 2026Review
- A Closed-Loop-Capable Neural Interface Platform for Deep Brain Modulation via Integrated Non-Viral Gene Delivery, NIR Optogenetics, and Electrophysiological Recording.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
This paper presents a thin-film, three-dimensional (3D) opto-electro array featuring four addressable microscale light-emitting diodes (LEDs) for surface cortex illumination and nine penetrating electrodes for simultaneous recording of light-evoked neural activities. Inspired by the origami concept, we have developed a meticulously designed "bridge+trench" structure that facilitates the transformation of the array from 2D to 3D while preventing damage to the thin film metal. Prior to device transformation, the shape and dimensions of the 2D array can be customized, enhancing its versatility for various applications. In addition, the arched base offers strong mechanical support to facilitate the direct insertion of the probe into tissue without any mechanical reinforcement. The array was encapsulated using polyimide and epoxy to ensure mechanical flexibility and biocompatibility of the device. The efficacy of the device was evaluated through comprehensive in vitro and in vivo characterization.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.