Evidence map›Paper›PMID 40329201›Full record

SynthesisBMC gastroenterology2025

Association between adhering to a dietary approach to stop hypertension and risk of colorectal cancer: a systematic review and meta-analysis.

Mohammad Mehdi Abbasi, Paria Babaahmadi, Fateme Nozari, Farbod Khosravi, Zahra Golkar, Zahra Tavasoli, Venus Alizadeh, Marieh Nouriani, Mohammadsadegh Jafari, Niloufar Shabani and 3 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mohammad Mehdi Abbasi *Student Research Committee, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Paria Babaahmadi *Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Fateme Nozari *Student Research Committee, Tehran University of Medical Sciences, Tehran, Iran.
Farbod KhosraviShahid Beheshti University of Medical Sciences, Tehran, Iran.
Zahra GolkarStudent Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
Zahra TavasoliStudent Research Committee, School of Dentistry, Islamic Azad University, IAU (Khorasgan Branch), Isfahan, Iran.
Venus AlizadehShahid Beheshti University of Medical Sciences, Tehran, Iran.
Marieh NourianiBabol University of Medical Sciences, Babol, Iran.
Mohammadsadegh JafariUniversal Scientific Education and Research Network (USERN), Tehran, Iran.
Niloufar ShabaniSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hadis Hashemi NezhadStudent Research Committee, Jondishapoor University of Medical Science, Ahvaz, Iran.
Hossein SoltaninejadDepartment of Stem Cells Technology and Tissue Regeneration, Faculty of Interdisciplinary Science and Technologies, Tarbiat Modares University, Tehran, Iran. hossein.soltani@modares.ac.ir.
Mohammad RahmanianStudent Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. mmdrahmanian@sbmu.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColorectal cancer (CRC) is a high incidence cancer and health problem influenced by many factors emphasizes on the importance of identifying risk factors which can be modified. A dietary approach to stop hypertension (DASH) style promotes a balanced nutrition approach that might have effects on CRC. The aim of this study was to analyze existing evidence on the DASH diet's association with CRC.

methodsDatabases, including Scopus, Web of Science, and PubMed, were searched to identify eligible studies up to March 2025. Observational studies investigating the association between adherence to the DASH diet and CRC were included. Effect sizes (ESs) and their confidence intervals (CIs) from fully adjusted models were extracted for the meta-analysis. A random-effects model was employed to calculate the combined ES and assess the relationship between the DASH diet and CRC. The publication bias was assessed using Egger's test and heterogeneity between studies was examined using the I

resultsFourteen studies were included in this study. Adherence to DASH diet reduced CRC risk (RR = 0.81, 95% CI: 0.73-0.89). Subgroup analyses found consistent effects across cohorts and various factors, with no publication bias. For rectal cancer (RC), adherence to DASH dietary pattern reduced risk of RC (RR = 0.75, 95% CI: 0.66-0.86), particularly in males and cohort studies. Colon cancer risk was also reduced (RR = 0.83, 95% CI: 0.79-0.88), with stronger effects in males and cohort studies. For colorectal adenoma, DASH showed a significant risk reduction (RR = 0.42, 95% CI: 0.22-0.80).

conclusionsOur results highlight that following the DASH diet has a significant effect on lowering the risk of CRC which aligns with previous research. These findings support recommendation of following the DASH diet pattern reduces the burden of CRC. PROSPERO, registration ID: CRD42024569140.

Indexed as

Colorectal NeoplasmsDietary Approaches To Stop HypertensionPatient ComplianceHumansHypertensionMaleRisk FactorsColonic neoplasmsColorectal neoplasmsDietary approaches to stop hypertensionMeta-analysisRectal neoplasms

Identifiers

PMID40329201
PMCPMC12054039

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.